SCHEMBL6528293

SCHEMBL6528293

CCS(=O)(=O)Cc1ccc2c(c1)OCO2

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
GAA P10253 2/20 0.52
HSD17B10 Q99714 1/20 0.52
CYP3A4 P08684 4/20 0.51
MAPT P10636 2/20 0.51
SLC6A2 P23975 3/20 0.51
SLC6A3 Q01959 3/20 0.51
CYP2D6 P10635 2/20 0.51
SLC6A1 P30531 1/20 0.51
TAAR1 Q96RJ0 3/20 0.50
SLC6A4 P31645 3/20 0.50
CMA1 P23946 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C19 P33261 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6510785 0.86 CYP3A4 (0.49) ALDH1A1GAAHSD17B10CYP3A4MAPT
SCHEMBL924831 0.84 ALDH1A1 (0.54) ALDH1A1GAAHSD17B10CYP3A4MAPT
SCHEMBL9146427 0.83 TAAR1 (0.56) ALDH1A1CYP3A4MAPTSLC6A2SLC6A3
SCHEMBL30311564 0.81 TAAR1 (0.56) ALDH1A1GAAHSD17B10CYP3A4MAPT
SCHEMBL6529898 0.80 TAAR1 (0.55) ALDH1A1GAAHSD17B10CYP3A4SLC6A2
SCHEMBL92784 0.77 TAAR1 (0.60) ALDH1A1GAACYP3A4MAPTSLC6A2
SCHEMBL529821 0.75 TAAR1 (0.62) ALDH1A1GAACYP3A4MAPTSLC6A2
SCHEMBL25968392 0.75 TAAR1 (0.54) ALDH1A1GAAHSD17B10CYP3A4MAPT
SCHEMBL9153832 0.75 MMP1 (0.59) ALDH1A1CYP3A4MAPTSLC6A2SLC6A3
SCHEMBL429483 0.74 TAAR1 (0.67) ALDH1A1CYP3A4MAPTSLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005070915-A1 1,3-BENZODIOXOL-5-YLMETHYL METHYL SULFONE AND ITS DERIVATIVES, PREPARATION METHOD THEREOF AND WHITENING COMPOSITION CONTAINING THE SAME HAN, SANG MIN (KR) 2005-08-04 WO claimed
WO-2005070915-A1 1,3-BENZODIOXOL-5-YLMETHYL METHYL SULFONE AND ITS DERIVATIVES, PREPARATION METHOD THEREOF AND WHITENING COMPOSITION CONTAINING THE SAME HAN, SANG MIN (KR) 2005-08-04 WO disclosed