Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ELOVL1 | Q9BW60 | 5/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528299 | 1.00 | GAA (0.43) | GAAABCB11HDAC6MAPTHTT | |
| SCHEMBL11260547 | 0.83 | GAA (0.38) | GAAABCB11HDAC6MAPTHTT | |
| SCHEMBL20422254 | 0.77 | HTT (0.45) | GAAABCB11HDAC6MAPTHTT | |
| SCHEMBL17261502 | 0.73 | NPC1 (0.53) | GAAHDAC6MAPTHTTTSHR | |
| SCHEMBL17261501 | 0.73 | NPC1 (0.53) | GAAHDAC6MAPTHTTTSHR | |
| SCHEMBL1060286 | 0.73 | P2RX7 (0.56) | GAAMAPTHTTTSHRHSD17B10 | |
| SCHEMBL19457031 | 0.72 | MAPT (0.49) | GAAABCB11HDAC6MAPTHTT | |
| SCHEMBL8642464 | 0.71 | FBP1 (0.47) | GAAMAPTHTTTSHRHSD17B10 | |
| SCHEMBL8551495 | 0.71 | FBP1 (0.47) | GAAMAPTHTTTSHRHSD17B10 | |
| SCHEMBL541634 | 0.70 | MAPT (0.55) | GAAABCB11HDAC6MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |