Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642464 | 1.00 | FBP1 (0.47) | FBP1HSP90AA1NPC1HTTMAPT | |
| SCHEMBL27884173 | 0.75 | MAP4K4 (0.49) | NPC1HTTMAPTMEN1KMT2A | |
| SCHEMBL1060286 | 0.74 | P2RX7 (0.56) | NPC1HTTMAPTMEN1KMT2A | |
| SCHEMBL17261502 | 0.74 | NPC1 (0.53) | NPC1HTTMAPTMEN1KMT2A | |
| SCHEMBL17261501 | 0.74 | NPC1 (0.53) | NPC1HTTMAPTMEN1KMT2A | |
| SCHEMBL8551772 | 0.73 | FBP1 (0.42) | FBP1HSP90AA1HTTMAPTMEN1 | |
| SCHEMBL8638984 | 0.73 | FBP1 (0.42) | FBP1HSP90AA1HTTMAPTMEN1 | |
| SCHEMBL7114840 | 0.71 | F2 (0.53) | HSP90AA1NPC1HTTMAPTMEN1 | |
| SCHEMBL6528301 | 0.71 | GAA (0.43) | NPC1HTTMAPTMEN1KMT2A | |
| SCHEMBL6528299 | 0.71 | GAA (0.43) | NPC1HTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833630-A4 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN INC (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5763470-A | Benzopyran compounds and methods for their use | SUGEN INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0833630-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | Sugen, Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996040110-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | disclosed |