Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536850 | 0.82 | LMNA (0.48) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL6525905 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL6526403 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL11450212 | 0.76 | KDM4E (0.39) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL2884818 | 0.76 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1192946 | 0.75 | F7 (0.47) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1171146 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL17513589 | 0.75 | TDP1 (0.47) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL6524736 | 0.75 | KIF11 (0.41) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL11020966 | 0.75 | SMN1; SMN2 (0.51) | ALDH1A1MAPTHPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575925-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056784-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | WO | disclosed |