Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.41 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.41 |
| ▸ | RPS17 | P08708 | 1/20 | 0.41 |
| ▸ | RPSA | P08865 | 1/20 | 0.41 |
| ▸ | RPS2 | P15880 | 1/20 | 0.41 |
| ▸ | RPL35A | P18077 | 1/20 | 0.41 |
| ▸ | RPL7 | P18124 | 1/20 | 0.41 |
| ▸ | RPL17 | P18621 | 1/20 | 0.41 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.41 |
| ▸ | RPS3 | P23396 | 1/20 | 0.41 |
| ▸ | RPS12 | P25398 | 1/20 | 0.41 |
| ▸ | RPL13 | P26373 | 1/20 | 0.41 |
| ▸ | RPL10 | P27635 | 1/20 | 0.41 |
| ▸ | RPL12 | P30050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Florfenicol SCHEMBL648517 | 1.00 | LMNA (0.76) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL652164 | 1.00 | LMNA (0.76) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL649266 | 1.00 | LMNA (0.76) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL648647 | 1.00 | LMNA (0.76) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL649955 | 0.99 | LMNA (0.77) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL4418722 | 0.93 | LMNA (0.84) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL650758 | 0.92 | LMNA (0.82) | LMNACYP3A4MEN1KMT2ATSHR | |
| Thiamphenicol SCHEMBL10911238 | 0.91 | LMNA (0.75) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL651494 | 0.88 | LMNA (0.88) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL49425 | 0.87 | LMNA (1.00) | LMNACYP3A4MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786167-B2 | Ester derivatives; in vivo saponification by endogenous enzymes; dosage efficiency | IDEXX LABORATORIES, INC. (US) | 2010-08-31 | — | — | US | claimed |
| EP-2181706-A2 | Florfenicol esters for treating bacterial infections | IDEXX LABORATORIES, INC. (US) | 2010-05-05 | — | — | EP | claimed |
| US-20080306152-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LBORATORIES, INC. (US) | 2008-12-11 | — | — | US | claimed |
| US-20080090912-A1 | Compositions containing prodrugs of florfenicol and methods of use | MURTHY YERRAMILLI V | 2008-04-17 | — | — | US | claimed |
| EP-1651202-A4 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LAB INC (US) | 2006-08-02 | — | — | EP | claimed |
| EP-1651202-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2006-05-03 | — | — | EP | claimed |
| WO-2005009429-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2005-02-03 | — | — | WO | claimed |
| US-20050014828-A1 | Compositions containing prodrugs of florfenicol and methods of use | IDEXX LABORATORIES, INC. | 2005-01-20 | — | — | US | claimed |
| US-8119667-B2 | Carbonates of fenicol antibiotics | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| EP-2181706-A3 | Florfenicol esters for treating bacterial infections | IDEXX LABORATORIES, INC. (US) | 2010-10-06 | — | — | EP | disclosed |
| US-7786167-B2 | Ester derivatives; in vivo saponification by endogenous enzymes; dosage efficiency | IDEXX LABORATORIES, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7786167-B2 | Ester derivatives; in vivo saponification by endogenous enzymes; dosage efficiency | IDEXX LABORATORIES, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| EP-2181706-A2 | Florfenicol esters for treating bacterial infections | IDEXX LABORATORIES, INC. (US) | 2010-05-05 | — | — | EP | disclosed |
| EP-2181706-A2 | Florfenicol esters for treating bacterial infections | IDEXX LABORATORIES, INC. (US) | 2010-05-05 | — | — | EP | disclosed |
| EP-1651202-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2006-05-03 | — | — | EP | disclosed |
| EP-1651202-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005009429-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2005-02-03 | — | — | WO | disclosed |
| WO-2005009429-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2005-02-03 | — | — | WO | disclosed |
| US-20050014828-A1 | Compositions containing prodrugs of florfenicol and methods of use | IDEXX LABORATORIES, INC. | 2005-01-20 | — | — | US | disclosed |
| US-20050014828-A1 | Compositions containing prodrugs of florfenicol and methods of use | IDEXX LABORATORIES, INC. | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306152-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | FAP, CYP3A5, CYP4F3 | LMNA 2883/4885CYP3A4 4/4885MEN1 3907/4885 |
| US-20050014828-A1 | Compositions containing prodrugs of florfenicol and methods of use | FAP, CYP3A5, CYP4F3 | LMNA 2883/4885CYP3A4 4/4885MEN1 3907/4885 |
| US-20080090912-A1 | Compositions containing prodrugs of florfenicol and methods of use | FAP, CYP3A5, CYP4F3 | LMNA 2883/4885CYP3A4 4/4885MEN1 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.