Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.84 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.45 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.45 |
| ▸ | RPS17 | P08708 | 1/20 | 0.45 |
| ▸ | RPSA | P08865 | 1/20 | 0.45 |
| ▸ | RPS2 | P15880 | 1/20 | 0.45 |
| ▸ | RPL35A | P18077 | 1/20 | 0.45 |
| ▸ | RPL7 | P18124 | 1/20 | 0.45 |
| ▸ | RPL17 | P18621 | 1/20 | 0.45 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.45 |
| ▸ | RPS3 | P23396 | 1/20 | 0.45 |
| ▸ | RPS12 | P25398 | 1/20 | 0.45 |
| ▸ | RPL13 | P26373 | 1/20 | 0.45 |
| ▸ | RPL10 | P27635 | 1/20 | 0.45 |
| ▸ | RPL12 | P30050 | 1/20 | 0.45 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Florfenicol SCHEMBL650944 | 0.95 | LMNA (0.79) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL649955 | 0.94 | LMNA (0.77) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL649266 | 0.93 | LMNA (0.76) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL652164 | 0.93 | LMNA (0.76) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL652835 | 0.93 | LMNA (0.76) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL648647 | 0.93 | LMNA (0.76) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL648517 | 0.93 | LMNA (0.76) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL650758 | 0.92 | LMNA (0.82) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL650814 | 0.92 | LMNA (0.95) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL3637832 | 0.92 | LMNA (1.00) | LMNACYP3A4MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113975404-A | Florfenicol polypeptide derivative and application thereof | 中国农业科学院兰州畜牧与兽药研究所 | 2022-01-28 | — | — | CN | claimed |
| CN-113975404-A | Florfenicol polypeptide derivative and application thereof | 中国农业科学院兰州畜牧与兽药研究所 | 2022-01-28 | — | — | CN | disclosed |
| EP-1696934-B1 | FLORFENICOL PRODRUG HAVING IMPROVED WATER SOLUBILITY | SCHERING PLOUGH LTD (CH) | 2013-05-29 | — | — | EP | disclosed |
| CN-101337916-B | Florfeniol sulfonic acid ester, salt thereof and method for preparing same | ZHANGJIAGANG HENGSHENG PHARMACEUTICAL CO LTD | 2011-02-16 | — | — | CN | disclosed |
| CN-100579532-C | Florfenicol prodrug having improved water solubility | SCHERING PLOUGH LTD | 2010-01-13 | — | — | CN | disclosed |
| US-7572777-B2 | Florfenicol prodrug having improved water solubility | SCHERING-PLOUGH ANIMAL HEALTH CORP. (US) | 2009-08-11 | — | — | US | disclosed |
| CN-101337916-A | Florfeniol sulfonic acid ester, salt thereof and method for preparing same | ZHANGJIAGANG HENGSHENG PHARMAC (CN) | 2009-01-07 | — | — | CN | disclosed |
| US-20070021387-A1 | Florfenicol prodrug having improved water solubility | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2007-01-25 | — | — | US | disclosed |
| CN-1897954-A | Florfenicol prodrug having improved water solubility | SCHERING PLOUGH ANIMAL HEALTH (CH) | 2007-01-17 | — | — | CN | disclosed |
| US-7153842-B2 | Florfenicol prodrug having improved water solubility | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1696934-A1 | FLORFENICOL PRODRUG HAVING IMPROVED WATER SOLUBILITY | Schering-Plough Ltd. (CH) | 2006-09-06 | — | — | EP | disclosed |
| US-20050182031-A1 | Florfenicol prodrug having improved water solubility | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2005-08-18 | — | — | US | disclosed |
| WO-2005063257-A1 | FLORFENICOL PRODRUG HAVING IMPROVED WATER SOLUBILITY | SCHERING-PLOUGH LTD. (CH) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182031-A1 | Florfenicol prodrug having improved water solubility | FAP, PFAS, CYP4F3 | LMNA 3143/4885CYP3A4 26/4885MEN1 3391/4885 |
| US-20070021387-A1 | Florfenicol prodrug having improved water solubility | FAP, PFAS, CYP4F3 | LMNA 3143/4885CYP3A4 26/4885MEN1 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.