Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 10/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531235 | 1.00 | MEN1 (0.54) | MEN1MAPTKMT2ASLC5A1SLC5A2 | |
| SCHEMBL6528375 | 1.00 | MEN1 (0.54) | MEN1MAPTKMT2ASLC5A1SLC5A2 | |
| SCHEMBL2932597 | 0.86 | HTR6 (0.47) | MEN1MAPTKMT2ASLC5A1SLC5A2 | |
| SCHEMBL29092577 | 0.80 | SLC5A1 (0.55) | MEN1MAPTKMT2ASLC5A1SLC5A2 | |
| Hydrochloric Acid SCHEMBL6134453 | 0.79 | MAPT (0.53) | MEN1MAPTKMT2ASLC5A1SLC5A2 | |
| SCHEMBL5367153 | 0.78 | PLA2G2A (0.49) | MEN1MAPTKMT2ASLC5A1SLC5A2 | |
| SCHEMBL14280694 | 0.77 | SMO (0.55) | MEN1MAPTKMT2ASLC5A1SLC5A2 | |
| SCHEMBL27494197 | 0.74 | ALDH1A1 (0.59) | MEN1MAPTKMT2ASLC5A1SLC5A2 | |
| SCHEMBL16766513 | 0.74 | SLC5A1 (0.58) | MEN1MAPTKMT2ASLC5A1SLC5A2 | |
| SCHEMBL5206733 | 0.73 | SCD5 (0.47) | MEN1MAPTKMT2ASLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066157-A1 | 3-(PYROLIDIN-3-L) INDOLES AS 5-HT6 RECEPTOR MODULATORS | SUVEN LIFE SCIENCES (IN) | 2005-07-21 | — | — | WO | claimed |
| WO-2005066157-A1 | 3-(PYROLIDIN-3-L) INDOLES AS 5-HT6 RECEPTOR MODULATORS | SUVEN LIFE SCIENCES (IN) | 2005-07-21 | — | — | WO | disclosed |