Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 7/20 | 0.44 |
| ▸ | MMP1 | P03956 | 6/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526546 | 0.93 | HPGD (0.43) | CXCR3KEAP1TAS2R14NFE2L2PTGES | |
| SCHEMBL6528255 | 0.92 | TAS2R14 (0.48) | CXCR3KEAP1TAS2R14NFE2L2MMP13 | |
| SCHEMBL5397317 | 0.91 | MMP13 (0.51) | CXCR3KEAP1TAS2R14NFE2L2PTGES | |
| SCHEMBL6525406 | 0.91 | RORC (0.41) | TAS2R14MMP13MMP1MMP9ALDH1A1 | |
| SCHEMBL5438405 | 0.90 | MMP13 (0.48) | CXCR3MMP13MMP1MMP9LMNA | |
| SCHEMBL6529409 | 0.89 | BACE1 (0.43) | TAS2R14MMP13MMP1MMP9LMNA | |
| SCHEMBL9223594 | 0.89 | RORC (0.41) | TAS2R14MMP13MMP1MMP9ADAMTS4 | |
| SCHEMBL6526646 | 0.88 | TAS2R14 (0.41) | CXCR3TAS2R14LMNAADAMTS5 | |
| SCHEMBL6527557 | 0.88 | KMT2A (0.42) | TAS2R14MMP13MMP1MMP9NPSR1 | |
| SCHEMBL2581364 | 0.88 | CXCR3 (0.45) | CXCR3KEAP1TAS2R14NFE2L2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3657002-B2 | — | — | 2005-06-08 | — | — | JP | claimed |
| WO-1994004492-A1 | HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1994-03-03 | — | — | WO | claimed |