Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528946 | 0.79 | THRA (0.39) | THRATHRBALDH1A1POLBMAPT | |
| SCHEMBL6506348 | 0.76 | KMT2A (0.40) | ALDH1A1POLBMAPTMMP12MEN1 | |
| SCHEMBL6505023 | 0.75 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MMP12MEN1KMT2A | |
| SCHEMBL6503746 | 0.75 | THRA (0.46) | THRATHRBALDH1A1MAPTMEN1 | |
| SCHEMBL12065158 | 0.72 | THRA (0.61) | THRATHRBALDH1A1POLBMAPT | |
| SCHEMBL11033278 | 0.72 | ALDH1A1 (0.45) | THRATHRBALDH1A1POLBMAPT | |
| SCHEMBL13192208 | 0.71 | ALDH1A1 (0.50) | THRATHRBALDH1A1POLBMAPT | |
| SCHEMBL10236930 | 0.71 | THRA (0.67) | THRATHRBALDH1A1POLBMAPT | |
| SCHEMBL8874714 | 0.70 | KMT2A (0.38) | ALDH1A1POLBMAPTSMN1; SMN2MMP12 | |
| SCHEMBL8874702 | 0.70 | KMT2A (0.38) | ALDH1A1POLBMAPTSMN1; SMN2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |