Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL6528944 | 0.79 | THRA (0.46) | THRATHRBALDH1A1POLBMAPT | |
| SCHEMBL6504727 | 0.79 | S1PR1 (0.45) | ALDH1A1MAPTMMP12 | |
| SCHEMBL6500407 | 0.78 | ACACB (0.43) | MAPTRAB9ASMN1; SMN2MMP12TP53 | |
| SCHEMBL6529512 | 0.78 | MMP12 (0.40) | MMP12DPP4TDP1MMP13 | |
| SCHEMBL6529849 | 0.77 | MMP12 (0.35) | MMP12HIF1A | |
| SCHEMBL6531947 | 0.77 | DRD2 (0.37) | ALDH1A1POLBMMP12F2F10 | |
| SCHEMBL6527335 | 0.76 | TAAR1 (0.36) | POLBF2F10 | |
| SCHEMBL6530111 | 0.75 | SRC (0.38) | MMP12MMP13 | |
| SCHEMBL6531215 | 0.74 | ESR1 (0.37) | MAPTMMP12ABCB1 | |
| SCHEMBL6530119 | 0.74 | S1PR1 (0.44) | ALDH1A1MAPTSMN1; SMN2MMP12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |