Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3594548 | 0.98 | ACVR1 (0.42) | ACVR1BMPR1BBMPR1AACVRL1POLB | |
| SCHEMBL26476507 | 0.79 | PKM (0.55) | ACVR1BMPR1BBMPR1AACVRL1POLB | |
| SCHEMBL31251202 | 0.79 | MEN1 (0.50) | POLBMEN1KMT2APKMMAPT | |
| SCHEMBL13993447 | 0.79 | MEN1 (0.50) | POLBMEN1KMT2APKMMAPT | |
| SCHEMBL22667344 | 0.78 | ALDH1A1 (0.50) | ACVR1BMPR1BBMPR1AACVRL1POLB | |
| SCHEMBL13234017 | 0.78 | BMPR1B (0.40) | ACVR1BMPR1BBMPR1AACVRL1MEN1 | |
| SCHEMBL5862203 | 0.78 | ATAD2 (0.47) | MEN1KMT2APKMCNR1GPR55 | |
| SCHEMBL30954700 | 0.77 | OPRL1 (0.48) | ACVR1BMPR1BBMPR1AACVRL1POLB | |
| SCHEMBL21032697 | 0.77 | PKM (0.39) | ACVR1POLBNOX1MEN1KMT2A | |
| SCHEMBL2488961 | 0.77 | OPRL1 (0.48) | POLBMEN1KMT2ANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082900-A2 | OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |