Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268446 | 0.81 | MAPT (0.41) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29728425 | 0.79 | ALOX12 (0.43) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL28802526 | 0.79 | ALOX12 (0.43) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL65301 | 0.78 | MAPT (0.54) | ATMPTGS2ALDH1A1MAPTMEN1 | |
| SCHEMBL19429628 | 0.76 | ALDH1A1 (0.45) | PTGS2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27401270 | 0.73 | AVPR1A (0.43) | ATMALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4886001 | 0.71 | ALDH1A1 (0.56) | ATMALDH1A1MEN1KMT2AGSK3A | |
| SCHEMBL3970588 | 0.69 | GSK3A (0.47) | PTGS2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL645648 | 0.69 | POLB (0.68) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9370346 | 0.68 | POLB (0.64) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851644-B2 | Heterocyclic metallocenes and polymerization catalysts | BASELL POLYOLEFINE GMBH (DE) | 2010-12-14 | — | — | US | disclosed |
| US-20090286945-A9 | Heterocyclic metallocenes and polymerization catalysts | EWEN JOHN A | 2009-11-19 | — | — | US | disclosed |
| US-20080090978-A1 | Heterocyclic metallocenes and polymerization catalysts | EWEN JOHN A | 2008-04-17 | — | — | US | disclosed |
| US-7238818-B2 | Heterocyclic metallocenes and polymerization catalysts | BASELL POLYOLEFINE GMBH (DE) | 2007-07-03 | — | — | US | disclosed |
| EP-1327636-B1 | Heterocyclic metallocenes and polymerisation catalysts | BASELL POLYOLEFINE GMBH (DE) | 2006-01-11 | — | — | EP | disclosed |
| US-20050192418-A1 | Heterocyclic metallocenes and polymerization catalysts | EQUISTAR CHEMICALS, LP | 2005-09-01 | — | — | US | disclosed |
| EP-1327636-A2 | Heterocyclic metallocenes and polymerisation catalysts | Basell Polyolefine GmbH (DE) | 2003-07-16 | — | — | EP | disclosed |
| CN-1113890-C | Heterocyclic metallocenes and polymerization catalysts | MONTELL TECHNOLOGY COMPANY BV (NL) | 2003-07-09 | — | — | CN | disclosed |
| EP-0938491-B1 | HETEROCYCLIC METALLOCENES AND POLYMERIZATION CATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2003-05-07 | — | — | EP | disclosed |
| CN-1244201-A | Heterocyclic metallocenes and polymerization catalysts | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-02-09 | — | — | CN | disclosed |
| EP-0938491-A1 | HETEROCYCLIC METALLOCENES AND POLYMERIZATION CATALYSTS | Montell Technology Company B.V. (NL) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998022486-A1 | HETEROCYCLIC METALLOCENES AND POLYMERIZATION CATALYSTS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286945-A9 | Heterocyclic metallocenes and polymerization catalysts | GAK, ZYX, POLK | ATM 2305/4885PTGS2 776/4885ALDH1A1 2772/4885 |
| US-20050192418-A1 | Heterocyclic metallocenes and polymerization catalysts | GAK, INTS9, ZYX | ATM 1496/4885PTGS2 874/4885ALDH1A1 2590/4885 |
| US-20080090978-A1 | Heterocyclic metallocenes and polymerization catalysts | GAK, ZYX, POLK | ATM 2305/4885PTGS2 776/4885ALDH1A1 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.