Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 16/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500245 | 0.93 | SIGMAR1 (0.73) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL7268908 | 0.79 | SIGMAR1 (0.79) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL5862113 | 0.79 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL7549641 | 0.79 | KCNA3 (0.59) | SIGMAR1POLBL3MBTL1KMT2A | |
| SCHEMBL4951743 | 0.79 | SIGMAR1 (0.64) | SIGMAR1KMT2A | |
| SCHEMBL6505347 | 0.78 | EPHX1 (0.53) | SIGMAR1POLB | |
| Hydrochloric Acid SCHEMBL29640479 | 0.78 | SIGMAR1 (0.77) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL19086863 | 0.78 | SIGMAR1 (0.68) | SIGMAR1POLBKMT2A | |
| SCHEMBL6750438 | 0.78 | SIGMAR1 (0.77) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL28543008 | 0.78 | DPP7 (0.59) | SIGMAR1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009843-A1 | Medicine for inhibiting drug elimination pump | TRINE PHARMACEUTICALS, INC. | 2005-01-13 | — | — | US | disclosed |
| EP-1389463-A1 | MEDICINE FOR INHIBITING DRUG ELIMINATION PUMP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009843-A1 | Medicine for inhibiting drug elimination pump | ABCB11, ATP6AP1, HRH2 | SIGMAR1 339/4885POLB 3610/4885L3MBTL1 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.