Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4818536 | 0.85 | MBOAT4 (0.45) | MBOAT4ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL3276173 | 0.85 | ALDH1A1 (0.39) | MBOAT4ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL5096454 | 0.84 | ALDH1A1 (0.46) | ALDH1A1POLBKMT2ATSHRMAPK1 | |
| SCHEMBL14489594 | 0.83 | MAPK1 (0.45) | MBOAT4ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL14573289 | 0.80 | ENPP1 (0.38) | MBOAT4ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL5090587 | 0.80 | MAPK1 (0.38) | ALDH1A1POLBKMT2ATSHRMAPK1 | |
| SCHEMBL7962066 | 0.80 | LMNA (0.42) | ALDH1A1POLBKMT2ATSHRMAPK1 | |
| SCHEMBL5096856 | 0.80 | ALDH1A1 (0.38) | MBOAT4ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL5096836 | 0.80 | ALDH1A1 (0.36) | MBOAT4ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL4819849 | 0.80 | MBOAT4 (0.44) | MBOAT4ALDH1A1POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969730-B2 | Amines as histamine-3 receptor ligands and their therapeutic applications | ABBOTT LABORATORIES (US) | 2005-11-29 | — | — | US | disclosed |
| US-6855718-B2 | 7-(r)-aminotriazolopyrimidines, the production thereof and use of the same for combatting phytopathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-15 | — | — | US | disclosed |
| US-20040110771-A1 | 7-(r)-aminotriazolopyrimidines, the production thereof and use of the same for combatting phytopathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110771-A1 | 7-(r)-aminotriazolopyrimidines, the production thereof and use of the same for combatting phytopathogenic fungi | CBR1, CBR3, DPM1 | MBOAT4 3302/4885ALDH1A1 1806/4885POLB 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.