Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 4/20 | 0.37 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408922 | 0.85 | SETDB1 (0.39) | KMT2ASETDB1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6530775 | 0.84 | NPC1 (0.51) | TGM2KMT2AMEN1SETDB1MAPT | |
| SCHEMBL9408804 | 0.82 | SETDB1 (0.36) | SETDB1MAPTHTTALDH1A1LMNA | |
| SCHEMBL11396584 | 0.82 | RAB9A (0.38) | TGM2KMT2AMEN1MAPTUSP2 | |
| SCHEMBL6530701 | 0.82 | PTPN1 (0.39) | TGM2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL346033 | 0.81 | SETDB1 (0.40) | KMT2AMEN1PKMSETDB1MAPT | |
| SCHEMBL11401422 | 0.81 | NPC1 (0.38) | TGM2KMT2AMEN1MAPTUSP2 | |
| SCHEMBL9408880 | 0.81 | SETDB1 (0.36) | SETDB1ALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL5679060 | 0.78 | NPC1 (0.35) | TGM2KMT2AMEN1MAPTUSP2 | |
| SCHEMBL1264757 | 0.77 | GABRA1 (0.51) | KMT2AMEN1PKMMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8899745-B2 | Ophthalmic lenses modified with functional groups and methods of making thereof | NOVARTIS AG (CH) | 2014-12-02 | — | — | US | disclosed |
| JP-2007204593-A | ORGANIC DYE USING BENZOTRIAZOLE DERIVATIVE | SHIPRO KASEI KAISHA LTD | 2007-08-16 | — | — | JP | disclosed |