Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.34 |
| ▸ | RAF1 | P04049 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16972790 | 0.82 | ALDH1A1 (0.43) | POLBMAPTMMP12ALDH1A1KMT2A | |
| SCHEMBL4105175 | 0.78 | NR3C2 (0.44) | MMP12ALDH1A1KMT2ANR3C2PGR | |
| SCHEMBL27434589 | 0.75 | MMP12 (0.38) | MAPTMMP12ALDH1A1KMT2ANR3C2 | |
| SCHEMBL27076356 | 0.75 | MMP12 (0.38) | MAPTMMP12ALDH1A1KMT2ANR3C2 | |
| SCHEMBL29961692 | 0.75 | MMP12 (0.38) | MAPTMMP12ALDH1A1KMT2ANR3C2 | |
| SCHEMBL1163368 | 0.74 | TDP2 (0.51) | MAPTALDH1A1KMT2APGRGAA | |
| SCHEMBL30806805 | 0.73 | POLB (0.51) | POLBMAPTMMP12ALDH1A1KMT2A | |
| SCHEMBL282326 | 0.73 | POLB (0.51) | POLBMAPTMMP12ALDH1A1KMT2A | |
| SCHEMBL2675271 | 0.73 | KIF11 (0.42) | ALDH1A1KMT2APGRTDP2HIF1A | |
| SCHEMBL17478775 | 0.71 | TDP2 (0.38) | MAPTALDH1A1KMT2APGRTDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |