Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | PDE9A | O76083 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528295 | 0.93 | LMNA (0.44) | LMNAMEN1KMT2ATP53PDE9A | |
| SCHEMBL6530969 | 0.89 | OGFRL1 (0.44) | LMNAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6530970 | 0.88 | L3MBTL1 (0.55) | LMNAMEN1KMT2ATP53PDE9A | |
| SCHEMBL6528420 | 0.86 | OGFRL1 (0.47) | OPRM1OPRD1OPRK1OPRL1OGFRL1 | |
| SCHEMBL6532558 | 0.84 | L3MBTL1 (0.41) | LMNAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6528391 | 0.83 | OPRM1 (0.41) | LMNAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6528752 | 0.83 | L3MBTL1 (0.42) | LMNAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6532520 | 0.82 | ALDH1A1 (0.47) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6530899 | 0.81 | OPRM1 (0.43) | TP53OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6530894 | 0.81 | OGFRL1 (0.46) | OPRM1OPRD1OPRK1OPRL1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019186-A1 | 2-AMINOBENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF HIV/AIDS | BAYER HEALTHCARE AG (DE) | 2005-03-03 | — | — | WO | disclosed |