Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788007 | 0.80 | TSHR (0.60) | MAPTTSHRALDH1A1GAAKDM4E | |
| SCHEMBL7111084 | 0.78 | PPARG (0.46) | MAPTTSHRALDH1A1GAARAB9A | |
| SCHEMBL7111821 | 0.78 | PPARG (0.46) | MAPTTSHRALDH1A1GAARAB9A | |
| SCHEMBL7107216 | 0.78 | TSHR (0.48) | MAPTTSHRALDH1A1GAARAB9A | |
| SCHEMBL7105914 | 0.76 | ALDH1A1 (0.47) | MAPTTSHRALDH1A1GAARAB9A | |
| SCHEMBL7196291 | 0.76 | TSHR (0.45) | MAPTTSHRALDH1A1KDM4EHTT | |
| SCHEMBL5438445 | 0.75 | MAPT (0.46) | MAPTTSHRALDH1A1GAAKDM4E | |
| SCHEMBL7035980 | 0.74 | PPARG (0.61) | MAPTTSHRALDH1A1HPGDPOLB | |
| SCHEMBL11787640 | 0.74 | ALDH1A1 (0.58) | MAPTTSHRALDH1A1RAB9AHPGD | |
| SCHEMBL11787186 | 0.74 | LTA4H (0.59) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049589-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA, DIABETES, OBESITY AND SIMILAR DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2005-06-02 | — | — | WO | disclosed |