Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111084 | 0.93 | PPARG (0.46) | TSHRALDH1A1MAPTPOLBHPGD | |
| SCHEMBL7111821 | 0.93 | PPARG (0.46) | TSHRALDH1A1MAPTPOLBHPGD | |
| SCHEMBL7107216 | 0.83 | TSHR (0.48) | TSHRALDH1A1MAPTPOLBHPGD | |
| SCHEMBL7105914 | 0.78 | ALDH1A1 (0.47) | TSHRALDH1A1MAPTPOLBHPGD | |
| SCHEMBL11787186 | 0.78 | LTA4H (0.59) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL11787640 | 0.78 | ALDH1A1 (0.58) | TSHRALDH1A1MAPTPOLBHPGD | |
| SCHEMBL7110525 | 0.77 | PPARG (0.57) | TSHRALDH1A1MAPTPOLBHPGD | |
| SCHEMBL6531313 | 0.76 | MAPT (0.48) | TSHRALDH1A1MAPTPOLBHPGD | |
| SCHEMBL12642701 | 0.75 | ALDH1A1 (0.54) | TSHRALDH1A1MAPTPOLBHPGD | |
| SCHEMBL5430363 | 0.75 | PPARG (0.48) | TSHRALDH1A1MAPTPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006022-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-01-23 | — | — | WO | claimed |