Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6130494 | 0.80 | NOS2 (0.50) | NOS2 | |
| SCHEMBL7736011 | 0.77 | NOS2 (0.36) | NOS2ARG1ARG2 | |
| SCHEMBL4200797 | 0.74 | ARG1 (0.45) | ARG1ARG2 | |
| SCHEMBL8192140 | 0.73 | ARG1 (0.47) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL8178078 | 0.73 | ARG1 (0.44) | NOS2ARG1ARG2 | |
| SCHEMBL7067880 | 0.71 | GGT1 (0.31) | — | |
| SCHEMBL7074563 | 0.71 | GGT1 (0.31) | — | |
| SCHEMBL7617170 | 0.71 | NOS1 (0.47) | NOS2 | |
| SCHEMBL7067866 | 0.71 | GGT1 (0.31) | — | |
| SCHEMBL6472209 | 0.71 | GGT1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025620-A2 | COMBINATION THERAPY WITH INHIBITORS OF INDUCIBLE NITRIC OXIDE SYNTHASE AND ALKYLATING AGENTS | PHARMACIA CORPORATION (US) | 2005-03-24 | — | — | WO | disclosed |