SCHEMBL6531941

SCHEMBL6531941

CCCCCCC=C1CC(C)OC1=O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 12/20 0.51
PPARG P37231 4/20 0.50
TYR P14679 1/20 0.42
PRKD3 O94806 2/20 0.42
PRKCG P05129 2/20 0.42
PRKCB P05771 2/20 0.42
PRKCH P24723 2/20 0.42
PRKCE Q02156 2/20 0.42
PRKCQ Q04759 2/20 0.42
PRKCD Q05655 2/20 0.42
PRKD1 Q15139 2/20 0.42
ABHD16A O95870 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20057474 1.00 PRKCA (0.51) PRKCAPPARGTYRPRKD3PRKCG
SCHEMBL666234 1.00 PRKCA (0.51) PRKCAPPARGTYRPRKD3PRKCG
SCHEMBL665964 1.00 PRKCA (0.51) PRKCAPPARGTYRPRKD3PRKCG
SCHEMBL663160 1.00 PRKCA (0.51) PRKCAPPARGTYRPRKD3PRKCG
SCHEMBL10186551 1.00 PRKCA (0.51) PRKCAPPARGTYRPRKD3PRKCG
SCHEMBL10186552 1.00 PRKCA (0.51) PRKCAPPARGTYRPRKD3PRKCG
SCHEMBL664841 1.00 PRKCA (0.51) PRKCAPPARGTYRPRKD3PRKCG
SCHEMBL9254632 1.00 PRKCA (0.51) PRKCAPPARGTYRPRKD3PRKCG
SCHEMBL10186550 1.00 PRKCA (0.51) PRKCAPPARGTYRPRKD3PRKCG
SCHEMBL21182172 1.00 PRKCA (0.51) PRKCAPPARGTYRPRKD3PRKCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265330-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2023-08-24 US disclosed
US-20230265330-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2023-08-24 US disclosed
US-11674067-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2023-06-13 US disclosed
US-11674067-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2023-06-13 US disclosed
US-20180127628-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2018-05-10 US disclosed
US-20180100092-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2018-04-12 US disclosed
US-20180100093-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2018-04-12 US disclosed
US-9890311-B2 Compositions comprising fluoroolefins and uses thereof THE CHEMOURS COMPANY FC, LLC (US) 2018-02-13 US disclosed
US-9879165-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2018-01-30 US disclosed
US-9670393-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2017-06-06 US disclosed
US-7198728-B2 1-ethoxy-1,1,2,2,3,3,4,4,4,-nonafluorobutane refrigerant compositions comprising a hydrocarbon and uses thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-03 US disclosed
US-7198728-B2 1-ethoxy-1,1,2,2,3,3,4,4,4,-nonafluorobutane refrigerant compositions comprising a hydrocarbon and uses thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-03 US disclosed
US-7157020-B2 Refrigerant compositions comprising performance enhancing additives E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-01-02 US disclosed
WO-2005014565-A2 CIS-3,5-DISUBSTITUTED-DIHYDRO-FURAN-2-ONES AND THE PREPARATION AND USE THEREOF E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-02-17 WO disclosed
US-5416224-A Reaction of acetyldihydro-2-(3H)-furanone with aldehyde and alkali metal hydroxide HENKEL CORPORATION (US) 1995-05-16 US disclosed
EP-0559789-A1 PROCESS FOR THE PREPARATION OF $g(a)-ALKYL LACTONES HENKEL CORPORATION (US) 1993-09-15 EP disclosed
US-5231192-A Reacting an a-acyl lactone, an aldehyde and an alkali metal hydroxide; hydrogenation HENKEL CORPORATION (US) 1993-07-27 US disclosed
WO-1992010487-A1 PROCESS FOR CONVERTING α-ACYL-SUBSTITUTED LACTONES TO α-ALKYLIDENE-SUBSTITUTED LACTONES HENKEL CORPORATION (US) 1992-06-25 WO disclosed
WO-1992009590-A1 PROCESS FOR THE PREPARATION OF α-ALKYL LACTONES HENKEL CORPORATION (US) 1992-06-11 WO disclosed
US-4980342-A Process for the preparation of α-alkyl lactones HENKEL CORPORATION (US) 1990-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180127628-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF GFPT1, PFAS, TRMT1 PRKCA 4469/4885PPARG 2047/4885TYR 1155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.