Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529960 | 0.91 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TP53NR1I2HDAC3 | |
| SCHEMBL4904407 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2TP53LMNAHTT | |
| SCHEMBL5930774 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2TP53MAPTHTT | |
| SCHEMBL4906622 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TP53NR1I2MAPT | |
| SCHEMBL6530253 | 0.75 | LNPEP (0.47) | LMNA | |
| SCHEMBL4903867 | 0.72 | TDP1 (0.46) | ALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL4908583 | 0.72 | HTT (0.48) | ALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL4900891 | 0.72 | MAPT (0.51) | ALDH1A1SMN1; SMN2TP53MAPTLMNA | |
| SCHEMBL4895165 | 0.72 | LMNA (0.40) | ALDH1A1SMN1; SMN2TP53NR1I2HDAC3 | |
| SCHEMBL4895638 | 0.72 | ERBB2 (0.44) | ALDH1A1SMN1; SMN2TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288340-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER INC | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288340-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PPARA, PPARG, PPARD | ALDH1A1 2956/4885SMN1; SMN2 3404/4885TP53 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.