Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532295 | 0.87 | PTPN1 (0.53) | POLBKMT2A | |
| SCHEMBL19748 | 0.86 | KMT2A (0.61) | POLBKMT2ACNR1 | |
| SCHEMBL30677473 | 0.81 | MEN1 (0.58) | KMT2AMEN1 | |
| SCHEMBL4560140 | 0.81 | RAB9A (0.57) | KMT2AMEN1AHR | |
| SCHEMBL28118358 | 0.79 | KMT2A (0.54) | POLBKMT2ACNR1 | |
| SCHEMBL6003890 | 0.78 | GRM4 (0.64) | POLBKMT2AMEN1 | |
| SCHEMBL20227586 | 0.75 | KCNK3 (0.79) | MGLLADORA3POLBKMT2AMEN1 | |
| SCHEMBL23246073 | 0.75 | GRM4 (0.57) | ADORA3POLBKMT2AMEN1 | |
| Biphenyl SCHEMBL27870431 | 0.74 | LMNA (0.43) | — | |
| SCHEMBL23246094 | 0.74 | RAB9A (0.55) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |