Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 4/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 2/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19748 | 0.90 | KMT2A (0.61) | PTPN1KMT2ASMN1; SMN2POLBNPC1 | |
| SCHEMBL6532409 | 0.87 | MGLL (0.55) | KMT2APOLB | |
| SCHEMBL28118358 | 0.83 | KMT2A (0.54) | KMT2ASMN1; SMN2POLBNPC1ALDH1A1 | |
| SCHEMBL23246023 | 0.82 | NPC1 (0.53) | KMT2ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL18027798 | 0.81 | RAB9A (0.54) | SMN1; SMN2POLBNPC1ALDH1A1HTT | |
| SCHEMBL16692723 | 0.81 | KMT2A (0.44) | KMT2ASMN1; SMN2POLBNPC1MITF | |
| SCHEMBL168618 | 0.81 | MEN1 (0.63) | PTPN1KMT2ASMN1; SMN2NPC1MITF | |
| SCHEMBL11041868 | 0.79 | KDM4E (0.55) | KMT2AALDH1A1HTT | |
| SCHEMBL23246003 | 0.78 | GAA (0.63) | KMT2ASMN1; SMN2NPC1RAB9A | |
| Biphenyl SCHEMBL27870431 | 0.78 | LMNA (0.43) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |