Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273873 | 0.94 | GLA (0.64) | GLAL3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL1272576 | 0.90 | LMNA (0.61) | GLAL3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL1273830 | 0.89 | GLA (0.41) | GLAL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL1272569 | 0.86 | ALDH1A1 (0.48) | GLAL3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL1273710 | 0.83 | GLA (0.48) | GLAL3MBTL1LMNASMN1; SMN2TSHR | |
| SCHEMBL6532488 | 0.81 | CA12 (0.46) | SMN1; SMN2HTTRAB9APOLBMEN1 | |
| SCHEMBL1273266 | 0.76 | MAPT (0.61) | LMNASMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL1273704 | 0.75 | ALDH1A1 (0.46) | ALDH1A1POLBMAPT | |
| SCHEMBL16085874 | 0.75 | NPC1 (0.51) | GLAL3MBTL1SMN1; SMN2HTTTSHR | |
| SCHEMBL1273818 | 0.74 | MAPT (0.44) | SMN1; SMN2ALDH1A1MAPK1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110038850-A1 | G Protein-Coupled Receptor and Modulators Thereof For The Treatment of Gaba-Related Neurological Disorders Including Sleep-Related Disorders | ARENA PHARMACEUTICALS, INC. | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110038850-A1 | G Protein-Coupled Receptor and Modulators Thereof For The Treatment of Gaba-Related Neurological Disorders Including Sleep-Related Disorders | BRS3, GPR3, GABRA3 | GLA 3619/4885L3MBTL1 2354/4885LMNA 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.