SCHEMBL65325

SCHEMBL65325

COC(=O)CN1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
TDP1 Q9NUW8 1/20 0.53
GAA P10253 1/20 0.50
CYP2D6 P10635 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
HTT P42858 2/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28645405 0.98 ALDH1A1 (0.56) ALDH1A1TDP1GAACYP2D6SMN1; SMN2
Hydrochloric Acid SCHEMBL27501008 0.98 ALDH1A1 (0.56) ALDH1A1TDP1GAACYP2D6SMN1; SMN2
SCHEMBL65441 0.98 ALDH1A1 (0.50) ALDH1A1TDP1GAACYP2D6SMN1; SMN2
Hydrochloric Acid SCHEMBL4391137 0.95 ALDH1A1 (0.53) ALDH1A1TDP1GAACYP2D6SMN1; SMN2
SCHEMBL28738942 0.93
Hydrochloric Acid SCHEMBL28912856 0.91 ALDH1A1 (0.49) ALDH1A1TDP1GAACYP2D6SMN1; SMN2
SCHEMBL70778 0.88 TSHR (0.46) ALDH1A1TDP1GAASMN1; SMN2KDM4E
SCHEMBL12379861 0.88 TSHR (0.46) ALDH1A1TDP1GAASMN1; SMN2KDM4E
SCHEMBL1133592 0.88
SCHEMBL19379914 0.85 ALDH1A1 (0.49) ALDH1A1TDP1GAACYP2D6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 666 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102216299-A 2, 5-diamino-substituted pyrido [4, 3-d] pyrimidines as autotaxin inhibitors against cancer MERCK PATENT GMBH 2011-10-12 CN claimed
EP-4660703-A2 METAL-CONTAINING FILM PATTERNING PROCESS Shin-Etsu Chemical Co., Ltd. (JP) 2025-12-10 EP disclosed
US-20250372377-A1 METAL-CONTAINING FILM PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-04 US disclosed
EP-3099304-B1 CHROMAN DERIVATIVES AND THEIR USE IN THE TREATMENT OF GLAUCOMA MAYO FOUND MEDICAL EDUCATION & RES (US) 2024-07-17 EP disclosed
US-12032287-B2 Resist material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-09 US disclosed
US-11994798-B2 Resist material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-28 US disclosed
EP-3686185-B1 FLUORENE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING HCV-RELATED DISEASE SEOUL NAT UNIV R&DB FOUNDATION (KR) 2023-12-13 EP disclosed
EP-4272825-A2 MTORC MODULATORS AND USES THEREOF Aeovian Pharmaceuticals, Inc. (US) 2023-11-08 EP disclosed
US-20230240960-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT ODDITY LABS, LLC 2023-08-03 US disclosed
US-11230557-B2 mTORC modulators and uses thereof AEOVIAN PHARMACEUTICALS, INC. (US) 2022-01-25 US disclosed
CN-1041203-C Process for producing pyrazolopyridine compound FUJISAWA PHARMACEUTICAL CO (JP) 1998-12-16 CN disclosed
CN-1201033-A Solid chemical compound, preparation method therefor and use in medicine JOHNSON MATTHEY CO LTD (GB) 1998-12-09 CN disclosed
CN-1183770-A Piperazine derivatives, medicaments containing these compounds, their use and processes for their preparation THOMAE GMBH DR K (DE) 1998-06-03 CN disclosed
EP-0800516-A1 FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME NIPPON STEEL CORPORATION (JP) 1997-10-15 EP disclosed
US-5661107-A ACYLUREA ACTIVE IN SMALL DOSAGE, HIGH SELECTIVITY DEGUSSA AKTIENGESELLSCHAFT (DE) 1997-08-26 US disclosed
CN-1156995-A Vitronectin receptor antagonists SMITHKLINE BEECHAM CORP (US) 1997-08-13 CN disclosed
WO-1997025323-A1 FIBRINOGEN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-07-17 WO disclosed
US-5576431-A Method for production of perfluoro-cyclic imine AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) 1996-11-19 US disclosed
WO-1996020172-A1 FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME NIPPON STEEL CORPORATION (JP) 1996-07-04 WO disclosed
CN-1085902-A Heterogeneous ring compound DEGUSSA (DE) 1994-04-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11230557-B2 mTORC modulators and uses thereof MTOR, RICTOR, RPTOR ALDH1A1 4766/4885TDP1 3445/4885GAA 2390/4885
US-20230240960-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT CUTA, COL14A1, DSG1 ALDH1A1 3302/4885TDP1 1034/4885GAA 1003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.