Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | AGT | P01019 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698703 | 0.90 | AGTR1 (0.47) | AGTR1AGTR2AGTALDH1A1SMN1; SMN2 | |
| SCHEMBL30956037 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2AGTALDH1A1SMN1; SMN2 | |
| SCHEMBL635 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2AGTALDH1A1SMN1; SMN2 | |
| SCHEMBL9024777 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2AGTTSHRKCNN4 | |
| SCHEMBL30316147 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2AGTTSHRKCNN4 | |
| SCHEMBL9383185 | 0.83 | AGTR1 (0.46) | AGTR1AGTR2AGTALDH1A1SMN1; SMN2 | |
| SCHEMBL8246839 | 0.82 | AGTR1 (0.50) | AGTR1AGTR2AGTALDH1A1HTT | |
| SCHEMBL9262004 | 0.82 | AGTR1 (0.46) | AGTR1AGTR2AGTALDH1A1SMN1; SMN2 | |
| SCHEMBL4246354 | 0.82 | AGTR1 (0.50) | AGTR1AGTR2AGTHTTPOLB | |
| SCHEMBL31050109 | 0.82 | AGTR1 (0.43) | AGTR1AGTR2AGTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910343-B1 | PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL | KRKA (SI) | 2014-10-29 | — | — | EP | claimed |
| EP-2173741-B1 | A PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL | LEK PHARMACEUTICALS (SI) | 2013-10-02 | — | — | EP | claimed |
| WO-2005049615-A1 | PYRAZOLO`1,5-A!`1,3,5! TRIAZIN -4-ONE DERIVATIVES AS CB1 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-06-02 | — | — | WO | claimed |
| US-5510354-A | HYPOTENSIVE AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0545912-A2 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1993-06-09 | — | — | EP | disclosed |