Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532434 | 0.90 | TYR (0.38) | RBP4PTGS2ALOX15L3MBTL1HTT | |
| SCHEMBL6533967 | 0.85 | ADRA1D (0.42) | ADRA1DADRA1AADRA1BPTGS2GRM5 | |
| SCHEMBL6529845 | 0.83 | GPR119 (0.46) | ADRA1DADRA1AADRA1BPTGS2GRM5 | |
| SCHEMBL5623713 | 0.81 | ALDH1A1 (0.45) | ADRA1DADRA1AADRA1BALOX15TYR | |
| SCHEMBL6527396 | 0.79 | ADRA1D (0.37) | ADRA1DADRA1AADRA1BPTGS2ALOX15 | |
| SCHEMBL6532028 | 0.78 | NOTUM (0.40) | RBP4GRM5 | |
| SCHEMBL6527383 | 0.78 | NOTUM (0.40) | RBP4GRM5 | |
| SCHEMBL6532725 | 0.74 | TYR (0.39) | PTGS2ALOX15HTTTYR | |
| SCHEMBL6534106 | 0.73 | KDM1A (0.44) | GRM5 | |
| SCHEMBL6532785 | 0.71 | RBP4 (0.40) | RBP4ADRA1DADRA1AADRA1BGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |