Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935742 | 0.99 | GPR84 (0.58) | DRD2DRD3KDM4EALDH1A1LMNA | |
| SCHEMBL5289613 | 0.96 | DRD2 (0.59) | DRD2DRD3KDM4EALDH1A1LMNA | |
| SCHEMBL7169528 | 0.90 | KDM4E (0.61) | DRD2DRD3KDM4EALDH1A1LMNA | |
| SCHEMBL4519869 | 0.87 | AKR1C3 (0.58) | DRD2DRD3KDM4EALDH1A1LMNA | |
| SCHEMBL24960989 | 0.86 | KDM4E (0.56) | DRD2DRD3KDM4EALDH1A1LMNA | |
| SCHEMBL4529329 | 0.86 | KDM4E (0.52) | DRD2DRD3KDM4EALDH1A1LMNA | |
| SCHEMBL22265093 | 0.86 | KDM4E (0.58) | DRD2DRD3KDM4EALDH1A1LMNA | |
| SCHEMBL29580772 | 0.84 | KDM4E (0.78) | DRD2DRD3KDM4EALDH1A1LMNA | |
| SCHEMBL42002 | 0.84 | KDM4E (0.78) | DRD2DRD3KDM4EALDH1A1LMNA | |
| SCHEMBL31310255 | 0.84 | RAB9A (0.75) | KDM4EALDH1A1LMNAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040073-A2 | SOLID PHASE SYNTHESIS OF 3-ARYL-2- INDOLYLCARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-05-06 | — | — | WO | disclosed |