Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.48 |
| ▸ | NOS1 | P29475 | 8/20 | 0.44 |
| ▸ | NOS2 | P35228 | 8/20 | 0.44 |
| ▸ | NOS3 | P29474 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | PGK2 | P07205 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23882858 | 0.88 | LOXL2 (0.48) | ENPP2PNMTLOXL2NOS1NOS2 | |
| SCHEMBL23882857 | 0.88 | LOXL2 (0.48) | ENPP2PNMTLOXL2NOS1NOS2 | |
| SCHEMBL21700186 | 0.87 | ENPP2 (0.54) | ENPP2PNMTLOXL2NOS1NOS2 | |
| SCHEMBL24792245 | 0.85 | ENPP2 (0.52) | ENPP2PNMTLOXL2NOS1NOS2 | |
| SCHEMBL27986627 | 0.83 | ENPP2 (0.50) | ENPP2PNMTLOXL2NOS1NOS2 | |
| SCHEMBL29607349 | 0.83 | ENPP2 (0.50) | ENPP2PNMTLOXL2NOS1NOS2 | |
| SCHEMBL8988941 | 0.83 | ENPP2 (0.50) | ENPP2PNMTLOXL2NOS1NOS2 | |
| SCHEMBL27317287 | 0.83 | PNMT (0.56) | ENPP2PNMTLOXL2NOS1NOS2 | |
| SCHEMBL28036349 | 0.82 | ENPP2 (0.48) | ENPP2PNMTLOXL2NOS1NOS2 | |
| SCHEMBL28036350 | 0.82 | ENPP2 (0.48) | ENPP2PNMTLOXL2NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037839-A1 | NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | ENTOMED (FR) | 2005-04-28 | — | — | WO | disclosed |