⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL325148 | 0.81 | CDK1 (0.33) | — | |
| SCHEMBL14548794 | 0.78 | CSNK2A1 (0.34) | — | |
| SCHEMBL7293078 | 0.78 | CSNK2A1 (0.31) | — | |
| SCHEMBL8588214 | 0.75 | KMT2A (0.38) | — | |
| SCHEMBL6533720 | 0.74 | DPP4 (0.51) | — | |
| SCHEMBL29853223 | 0.74 | — | — | |
| SCHEMBL16212194 | 0.73 | POLA1 (0.40) | — | |
| SCHEMBL3327705 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL2352412 | 0.72 | CSNK2A1 (0.41) | — | |
| SCHEMBL37383 | 0.71 | XDH (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227933-A1 | Treatment of bacterial induced diseases using DNA methyl transferase inhibitors | BENKOVIC STEPHEN J | 2005-10-13 | — | — | US | disclosed |
| US-20040259833-A1 | DNA methyl transferase inhibitors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2004-12-23 | — | — | US | disclosed |
| EP-1420021-A1 | DNA Methyltransferase inhibitors | The Penn State Research Foundation (US) | 2004-05-19 | — | — | EP | disclosed |
| CN-1370170-A | DNA methyltransferase inhibitors | PENN STATE RES FOUND (US) | 2002-09-18 | — | — | CN | disclosed |