Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | CTSG | P08311 | 2/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.33 |
| ▸ | CMA1 | P23946 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568919 | 1.00 | FOLH1 (0.38) | FOLH1KDM4ELMNAHTTNPSR1 | |
| SCHEMBL6980249 | 0.83 | FOLH1 (0.42) | FOLH1KDM4ELMNAHTTNPSR1 | |
| SCHEMBL6980245 | 0.83 | FOLH1 (0.42) | FOLH1KDM4ELMNAHTTNPSR1 | |
| SCHEMBL6980243 | 0.83 | FOLH1 (0.42) | FOLH1KDM4ELMNAHTTNPSR1 | |
| SCHEMBL8746478 | 0.76 | ELANE (0.49) | FOLH1MEN1KMT2APOLBELANE | |
| SCHEMBL7776782 | 0.76 | ELANE (0.49) | FOLH1MEN1KMT2APOLBELANE | |
| SCHEMBL4168099 | 0.74 | ALDH1A1 (0.38) | FOLH1LMNAMEN1KMT2APOLB | |
| SCHEMBL7777570 | 0.70 | ELANE (0.43) | KDM4EMEN1KMT2APOLBELANE | |
| SCHEMBL14344821 | 0.70 | POLB (0.37) | FOLH1KDM4ELMNAHTTMEN1 | |
| SCHEMBL14344945 | 0.70 | POLB (0.37) | FOLH1KDM4ELMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005070414-A1 | CONFORMATIONALLY CONSTRAINED PACLITAXEL ANALOGS AND THEIR USE AS ANTICANCER AND ANTI-ALZHEIMERS AGENTS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2005-08-04 | — | — | WO | disclosed |