Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677765 | 0.71 | NPC1 (0.53) | MMP3CLK2GSK3AGSK3BCDK9 | |
| SCHEMBL6244087 | 0.70 | KMT2A (0.54) | CDK9TLR8KMT2ANPC1ALDH1A1 | |
| SCHEMBL8310210 | 0.69 | ABL1 (0.36) | MMP3CLK2GSK3AGSK3BCDK9 | |
| SCHEMBL7491690 | 0.69 | ALDH1A1 (0.51) | MMP3CLK2GSK3AGSK3BCDK9 | |
| SCHEMBL6232908 | 0.69 | CDK5 (0.54) | MMP3CLK2GSK3AGSK3BCDK9 | |
| SCHEMBL3507059 | 0.65 | ALPL (0.42) | MMP3CLK2GSK3AGSK3BCDK9 | |
| SCHEMBL7474240 | 0.65 | TLR8 (0.48) | TLR8KMT2ASMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL4528378 | 0.65 | NPC1 (0.61) | KMT2ANPC1ALDH1A1MAPTSTAT1 | |
| SCHEMBL7488715 | 0.65 | ALDH1A1 (0.46) | MMP3CLK2GSK3AGSK3BCDK9 | |
| SCHEMBL11550029 | 0.65 | GSK3B (0.40) | MMP3CLK2GSK3AGSK3BCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | disclosed |