Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 2/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313967 | 0.76 | MAPK14 (0.38) | MAPTKMT2ATLR8MEN1KDM4E | |
| SCHEMBL8329490 | 0.74 | TLR8 (0.40) | NPC1ALDH1A1RAB9ATLR8SMN1; SMN2 | |
| SCHEMBL8334566 | 0.72 | TLR8 (0.36) | NPC1MAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL9148367 | 0.72 | SMN1; SMN2 (0.38) | CLK2CDK9LIMK1CDK5DYRK1A | |
| Hydrochloric Acid SCHEMBL9147162 | 0.70 | SMN1; SMN2 (0.37) | CLK2CDK9LIMK1CDK5DYRK1A | |
| SCHEMBL8312415 | 0.70 | SMN1; SMN2 (0.37) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6533996 | 0.69 | MMP3 (0.43) | ALPLALPICLK2GSK3AGSK3B | |
| SCHEMBL8310400 | 0.69 | MAPT (0.36) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9677765 | 0.67 | NPC1 (0.53) | CLK2GSK3AGSK3BCDK9LIMK1 | |
| SCHEMBL27834219 | 0.63 | NPC1 (0.46) | ALPLALPICLK2GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958295-A1 | SUBSTITUTED 2-(2,4(1H,3H)-PYRIMIDINDION-3-YL) BENZTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998033796-A1 | SUBSTITUTED 2-(2,4(1H,3H)-PYRIMIDINDION-3-YL) BENZTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-06 | — | — | WO | disclosed |