Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 5/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587665 | 0.77 | KMT2A (0.54) | KMT2AABCB1DRD2KCNH2MAPK1 | |
| SCHEMBL5064520 | 0.67 | CCR1 (0.50) | TACR1DRD4BCHEACHEBACE1 | |
| SCHEMBL814820 | 0.67 | PDPK1 (0.33) | DRD2 | |
| SCHEMBL28597653 | 0.67 | HTR1A (0.55) | KMT2AABCB1DRD2KCNH2 | |
| SCHEMBL20257085 | 0.67 | HRH3 (0.59) | SIGMAR1BCHEACHEBACE1 | |
| SCHEMBL13726788 | 0.67 | HRH3 (0.59) | SIGMAR1BCHEACHEBACE1 | |
| SCHEMBL3165269 | 0.65 | MLNR (0.63) | KCNH2 | |
| SCHEMBL13308196 | 0.65 | MLNR (0.63) | KCNH2 | |
| SCHEMBL3165020 | 0.65 | MLNR (0.63) | KCNH2 | |
| SCHEMBL19851034 | 0.65 | ALDH1A1 (0.56) | KMT2ABCHEACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042491-A1 | BENZAZEPINE DERIVATIVES AND METHODS OF PROPHYLAXIS OR TREATMENT OF 5HT2C RECEPTOR ASSOCIATED DISEASES | ARENA PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | claimed |