SCHEMBL6534166

SCHEMBL6534166

CCCCC(=O)C(O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@@H]1O

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AHCY P23526 4/20 0.48
EHMT1 Q9H9B1 1/20 0.48
POLB P06746 1/20 0.47
ENPP1 P22413 1/20 0.47
P2RY1 P47900 1/20 0.47
ADORA3 P0DMS8 2/20 0.45
HSP90AA1 P07900 1/20 0.45
HSP90B1 P14625 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA2B P29275 1/20 0.45
ADORA1 P30542 1/20 0.45
STING1 Q86WV6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6534224 0.96 EHMT1 (0.48) AHCYEHMT1POLBENPP1P2RY1
SCHEMBL6534188 0.85 AHCY (0.45) AHCYEHMT1POLBENPP1P2RY1
SCHEMBL5621212 0.84 AHCY (0.52) AHCYPOLBENPP1P2RY1ADORA3
SCHEMBL5621204 0.84 AHCY (0.52) AHCYPOLBENPP1P2RY1ADORA3
SCHEMBL6535196 0.84 EHMT1 (0.55) AHCYEHMT1POLBENPP1P2RY1
SCHEMBL6829732 0.84 ADORA3 (0.49) ADORA3
SCHEMBL66046 0.81 AHCY (0.57) AHCYPOLBENPP1P2RY1STING1
SCHEMBL28121858 0.80 AHCY (0.56) AHCYPOLBENPP1P2RY1STING1
SCHEMBL4451661 0.80 AHCY (0.59) AHCYPOLBENPP1P2RY1STING1
SCHEMBL5375731 0.80 EHMT1 (0.62) AHCYEHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040192635-A1 Acyl deoxyribonucleoside derivatives and uses thereof WELLSTAT THERAPEUTICS CORPORATION (US) 2004-09-30 US disclosed
US-6743782-B1 ACYL DERIVATIVE OF 2'-DEOXYADENOSINE; TREATING OR PREVENTING RADIATION, MUTAGEN AND SUNLIGHT-INDUCED CELLULAR DAMAGE, IMPROVING WOUND HEALING AND TISSUE REPAIR, AMELIORATING THE EFFECTS OF AGING; ENHANCE BIOAVAILABILITY WELLSTAT THERAPEUTICS CORPORATION 2004-06-01 US disclosed
US-6020320-A Acyl deoxyribonucleoside derivatives and uses thereof PRO-NEURON, INC. (US) 2000-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192635-A1 Acyl deoxyribonucleoside derivatives and uses thereof UNG, OGG1, NQO1 AHCY 221/4885EHMT1 1638/4885POLB 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.