SCHEMBL6534229

SCHEMBL6534229

CCCCCCCCCCCCCCCC(=O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)CC1O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.58
ENPP1 P22413 3/20 0.57
P2RY1 P47900 1/20 0.57
AHCY P23526 1/20 0.50
EHMT1 Q9H9B1 1/20 0.50
PRKACA P17612 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5358012 1.00 POLB (0.58) POLBENPP1P2RY1AHCYEHMT1
SCHEMBL5369306 0.96 POLB (0.59) POLBENPP1P2RY1AHCYEHMT1
SCHEMBL5359628 0.90 HIF1A (0.48) POLBENPP1P2RY1
SCHEMBL22875428 0.90 AHCY (0.47) POLBENPP1P2RY1AHCYEHMT1
SCHEMBL2691352 0.88 POLB (0.62) POLBENPP1P2RY1AHCYPRKACA
SCHEMBL8058699 0.86 POLB (0.64) POLBENPP1P2RY1AHCY
SCHEMBL1889395 0.86 POLB (0.64) POLBENPP1P2RY1AHCY
SCHEMBL8623380 0.85 POLB (0.65) POLBENPP1P2RY1AHCY
SCHEMBL3259692 0.85 POLB (0.65) POLBENPP1P2RY1AHCY
SCHEMBL7133529 0.85 POLB (0.59) POLBENPP1P2RY1AHCYPRKACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040192635-A1 Acyl deoxyribonucleoside derivatives and uses thereof WELLSTAT THERAPEUTICS CORPORATION (US) 2004-09-30 US disclosed
US-6743782-B1 ACYL DERIVATIVE OF 2'-DEOXYADENOSINE; TREATING OR PREVENTING RADIATION, MUTAGEN AND SUNLIGHT-INDUCED CELLULAR DAMAGE, IMPROVING WOUND HEALING AND TISSUE REPAIR, AMELIORATING THE EFFECTS OF AGING; ENHANCE BIOAVAILABILITY WELLSTAT THERAPEUTICS CORPORATION 2004-06-01 US disclosed
US-6020320-A Acyl deoxyribonucleoside derivatives and uses thereof PRO-NEURON, INC. (US) 2000-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192635-A1 Acyl deoxyribonucleoside derivatives and uses thereof UNG, OGG1, NQO1 POLB 46/4885ENPP1 122/4885P2RY1 1637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.