SCHEMBL653427

SCHEMBL653427

[c]1ccccc1Sc1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IFNAR1 P17181 1/20 0.42
ALDH1A1 P00352 6/20 0.41
LMNA P02545 3/20 0.41
MAPK1 P28482 2/20 0.41
NPY1R P25929 1/20 0.41
NPY2R P49146 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 1/20 0.37
RAD52 P43351 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
SIRT3 Q9NTG7 1/20 0.36
RECQL P46063 1/20 0.35
TYMS P04818 1/20 0.35
PDGFRB P09619 1/20 0.35
TSHR P16473 2/20 0.34
HSD17B10 Q99714 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16581496 0.96 IFNAR1 (0.44) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL40420 0.84 ALDH1A1 (0.38) IFNAR1ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL12079030 0.80 TRPM4 (0.38) ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A
SCHEMBL18065342 0.78 IFNAR1 (0.46) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL577858 0.77 IFNAR1 (0.60) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL31167972 0.77 IFNAR1 (0.60) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL30548749 0.75 IFNAR1 (0.58) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL2423602 0.75
SCHEMBL11141938 0.73 HAO1 (0.40) LMNA
SCHEMBL9500435 0.73 HAO1 (0.40) ALDH1A1LMNAKMT2AMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117683058-A Organic compound based on borazine as core and organic electroluminescent device comprising same 江苏三月科技股份有限公司 2024-03-12 CN claimed
US-20230422607-A1 AMINE COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-28 US claimed
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO claimed
WO-2022177288-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2022-08-25 WO claimed
CN-114656949-A Quantum dot-containing material and preparation method thereof, cross-linked material and preparation method thereof, and light-emitting device 三星显示有限公司 2022-06-24 CN claimed
CN-114561212-A Quantum dot-containing material, preparation method thereof, composition and light-emitting device 三星显示有限公司 2022-05-31 CN claimed
CN-114203937-A Arylamine compound, light-emitting device including same, and electronic apparatus including light-emitting device 三星显示有限公司 2022-03-18 CN claimed
CN-113838987-A Organic light emitting device 三星显示有限公司 2021-12-24 CN claimed
CN-111211247-A Organic light emitting device 三星显示有限公司 2020-05-29 CN claimed
JP-2007532665-A 2007-11-15 JP claimed
US-5985926-A VIRICIDES OF AMINE COMPOUNDS AND HYDROCARBONS CELL THERAPEUTICS, INC. (US) 1999-11-16 US claimed
US-5856331-A LYSOPHOSPHATIDIC ACYLTRANSFERASE INHIBITOR CELL THERAPEUTICS, INC. (US) 1999-01-05 US claimed
WO-1998034601-A2 METHOD FOR INHIBITING INTRACELLULAR VIRAL REPLICATION CELL THERAPEUTICS, INC. (US) 1998-08-13 WO claimed
EP-0739203-A1 METHOD FOR TREATING DISEASES MEDIATED BY CELLULAR PROLIFERATION IN RESPONSE TO PDGF, EGF, FGF AND VEGF CELL THERAPEUTICS, INC. (US) 1996-10-30 EP claimed
EP-0728003-A1 METHOD FOR PREVENTING TISSUE INJURY FROM HYPOXIA CELL THERAPEUTICS, INC. (US) 1996-08-28 EP claimed
EP-0676958-A1 METHOD FOR INHIBITING INTRACELLULAR VIRAL REPLICATION CELL THERAPEUTICS, INC. (US) 1995-10-18 EP claimed
WO-1995019171-A1 METHOD FOR TREATING DISEASES MEDIATED BY CELLULAR PROLIFERATION IN RESPONSE TO PDGF, EGF, FGF AND VEGF CELL THERAPEUTICS, INC. (US) 1995-07-20 WO claimed
WO-1995013075-A1 METHOD FOR PREVENTING TISSUE INJURY FROM HYPOXIA CELL THERAPEUTICS, INC. (US) 1995-05-18 WO claimed
WO-1995012396-A1 METHOD FOR INHIBITING INTRACELLULAR VIRAL REPLICATION CELL THERAPEUTICS, INC. (US) 1995-05-11 WO claimed
US-4675316-A FUNGICIDES ROHM AND HAAS COMPANY (US) 1987-06-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230422607-A1 AMINE COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME L1CAM, SLC1A2, AOC2 IFNAR1 1457/4885ALDH1A1 31/4885LMNA 1420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.