SCHEMBL653443

SCHEMBL653443

N#CCNCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
MAPT P10636 2/20 0.54
KDM4E B2RXH2 2/20 0.54
CYP3A4 P08684 1/20 0.54
MAOA P21397 1/20 0.50
MCL1 Q07820 1/20 0.48
CHRM2 P08172 1/20 0.48
GAA P10253 1/20 0.48
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SIGMAR1 Q99720 1/20 0.45
ADH1B P00325 1/20 0.45
ADH1C P00326 1/20 0.45
ADH1A P07327 1/20 0.45
ADH7 P40394 1/20 0.45
IDO1 P14902 2/20 0.44
THRB P10828 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21552856 0.98 MAPT (0.58) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL26670320 0.88 ALDH1A1 (0.53) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL13185941 0.80 CHRM2 (0.53) MEN1KMT2AMAPTKDM4ECYP3A4
Water SCHEMBL11666905 0.80 MEN1 (0.74) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL6663240 0.78 LMNA (0.59) MEN1KMT2ACYP3A4CHRM2
SCHEMBL11305587 0.78 CHRM2 (0.52) MEN1KMT2ATDP1KDM4ECHRM2
SCHEMBL2238594 0.78 CA12 (0.57) MAPTCYP3A4MAOAGAATSHR
SCHEMBL11445734 0.78 ANPEP (0.42) TDP1CYP3A4MAOATSHR
SCHEMBL421501 0.78 MEN1 (0.64) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL26672005 0.78 PYCR1 (0.66) MEN1KMT2AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117696115-A PDI/g-C 3 N 4 Z-type heterojunction catalyst and preparation method and application thereof 青岛科技大学 2024-03-15 CN claimed
CN-102531888-A Chemical synthesis method of 3,4,5-trimethoxy benzoyl chloride UNIV WENZHOU 2012-07-04 CN claimed
JP-6100543-A None JP disclosed
US-20250353853-A1 FLAVIVIRUS INHIBITORS IRBM S.P.A. (IT) 2025-11-20 US disclosed
EP-4532476-A1 FLAVIVIRUS INHIBITORS IRBM S.P.A. (IT) 2025-04-09 EP disclosed
CN-115515685-B EIF4E inhibitors and uses thereof 皮克医疗公司 2025-04-08 CN disclosed
CN-119707724-A Glycine (II)14Process for the preparation of C 长沙贝塔医药科技有限公司 2025-03-28 CN disclosed
EP-4523755-A2 QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS F. Hoffmann-La Roche AG (CH) 2025-03-19 EP disclosed
CN-119630645-A Flavivirus inhibitors IRBM股份公司 2025-03-14 CN disclosed
US-20250002495-A1 SPIRO-LACTAM NMDA MODULATORS AND METHODS OF USING SAME TENACIA BIOTECHNOLOGY HONG KONG CO LTD (HK) 2025-01-02 US disclosed
US-20240425476-A1 2-(2,4,5-SUBSTITUTED-ANILINO)PYRIMIDINE COMPOUNDS ASTRAZENECA AB (SE) 2024-12-26 US disclosed
US-4559371-A FOR PRINTING INKS AND PAINTS CIBA GEIGY CORPORATION (US) 1985-12-17 US disclosed
US-4525311-A O,O-Dialkyl-N-(benzyl or t-butyl)-N-cyanomethyl aminomethylphosphonates STAUFFER CHEMICAL COMPANY (US) 1985-06-25 US disclosed
EP-0117233-A1 Coloured photo-curable mouldings CIBA-GEIGY AG (CH) 1984-08-29 EP disclosed
US-4447446-A PESTICIDE, HERBICIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-05-08 US disclosed
US-4421693-A INSECTICIDES, MITICIDES OR NEMATOCIDES OTSUKA CHEMICAL CO., LTD. (JP) 1983-12-20 US disclosed
US-4413005-A 2,3-DIHYDRO-2,2-DIMETHYLBENZOFURAN-7-YL DERIVATIVES OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1983-11-01 US disclosed
EP-0088050-A2 Coloured photo-hardenable composition CIBA-GEIGY AG (CH) 1983-09-07 EP disclosed
EP-0059536-A2 Amide derivatives, processes for preparing them, their use as fungicides and pesticidal compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-08 EP disclosed
US-4134889-A Manufacture of glycinonitriles BASF AKTIENGESELLSCHAFT (DE) 1979-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425476-A1 2-(2,4,5-SUBSTITUTED-ANILINO)PYRIMIDINE COMPOUNDS EGFR, ERBB2, ERBB3 MEN1 4390/4885KMT2A 2198/4885TDP1 1247/4885
US-20250353853-A1 FLAVIVIRUS INHIBITORS SPINT2, EIF2AK2, DDX5 MEN1 3783/4885KMT2A 876/4885TDP1 2021/4885
US-20250002495-A1 SPIRO-LACTAM NMDA MODULATORS AND METHODS OF USING SAME GRIN1, GRIN2A, GRIN2C MEN1 1800/4885KMT2A 1269/4885TDP1 3836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.