Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.43 |
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.35 |
| ▸ | FEN1 | P39748 | 4/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178938 | 1.00 | NR3C1 (0.43) | NR3C1NR3C2PGRITGAVALOX5AP | |
| SCHEMBL3178425 | 0.80 | NR3C1 (0.44) | NR3C1NR3C2PGRITGAVALOX5AP | |
| SCHEMBL3177089 | 0.76 | MMP2 (0.55) | CA1CA2CA7CA9 | |
| SCHEMBL3180002 | 0.76 | RAB9A (0.51) | NR3C1TRPV3CA1CA2CA7 | |
| SCHEMBL3214337 | 0.76 | NR3C1 (0.39) | NR3C1NR3C2PGRITGAVCA1 | |
| SCHEMBL3220617 | 0.74 | NR3C1 (0.44) | NR3C1NR3C2PGRITGAVCA2 | |
| SCHEMBL3220629 | 0.74 | NR3C1 (0.45) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL5143422 | 0.74 | NR3C1 (0.39) | NR3C1NR3C2PGRITGAVALOX5AP | |
| SCHEMBL14132608 | 0.70 | CA1 (0.53) | NR3C1NR3C2PGRCA1CA2 | |
| SCHEMBL1168623 | 0.70 | PSEN1 (0.69) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006050-A1 | Substituted phenylsulfonamide inhibitors of beta amyloid production | WYETH (US) | 2004-01-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006050-A1 | Substituted phenylsulfonamide inhibitors of beta amyloid production | APP, BACE1, PSEN1 | NR3C1 2513/4885NR3C2 2576/4885PGR 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.