Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL9009598 | 1.00 | ALDH1A1 (0.37) | ALDH1A1 | |
| Ether SCHEMBL40006 | 1.00 | — | — | |
| Ether SCHEMBL28855718 | 1.00 | ALDH1A1 (0.37) | ALDH1A1 | |
| Ether SCHEMBL23704984 | 0.96 | ALDH1A1 (0.35) | ALDH1A1 | |
| Ether SCHEMBL16446730 | 0.96 | ALDH1A1 (0.35) | ALDH1A1 | |
| Ether SCHEMBL4526541 | 0.93 | ALDH1A1 (0.33) | ALDH1A1 | |
| Ether SCHEMBL3761236 | 0.93 | ALDH1A1 (0.40) | ALDH1A1 | |
| Ether SCHEMBL7408471 | 0.93 | ALDH1A1 (0.33) | ALDH1A1 | |
| Ether SCHEMBL4725961 | 0.93 | ALDH1A1 (0.33) | ALDH1A1 | |
| Ether SCHEMBL4526542 | 0.93 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094800-A4 | PEPTIDYL-PROLYL $i(CIS)-TRANS ISOMERASE INHIBITORS AND USES THEREFOR | SALK INST FOR BIOLOGICAL STUDI (US) | 2004-11-03 | — | — | EP | disclosed |
| US-20030096387-A1 | Peptidyl-prolyl cis-trans isomerase inhibitors and uses therefor | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2003-05-22 | — | — | US | disclosed |
| US-20010016346-A1 | PEDTIDYL-PROLYL CIS-TRANS ISOMERASE INHIBITORS AND USES THEREFORE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-08-23 | — | — | US | disclosed |
| EP-1094800-A2 | PEPTIDYL-PROLYL $i(CIS)-TRANS ISOMERASE INHIBITORS AND USES THEREFOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-1999063931-A9 | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE INHIBITORS AND USES THEREFOR | SALK INST FOR BIOLOGICAL STUDI (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-1999063931-A2 | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE INHIBITORS AND USES THEREFOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1999-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010016346-A1 | PEDTIDYL-PROLYL CIS-TRANS ISOMERASE INHIBITORS AND USES THEREFORE | PPIL1, PIN1, PPIL4 | ALDH1A1 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.