Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL27605341 | 0.94 | ASAH1 (0.54) | ALDH1A1KDM4EASAH1LMNASMN1; SMN2 | |
| Fenipentol SCHEMBL10795261 | 0.90 | ALDH1A1 (0.55) | ALDH1A1KDM4EASAH1LMNAPOLB | |
| Fenipentol SCHEMBL11573151 | 0.86 | LMNA (0.64) | ALDH1A1KDM4EASAH1LMNAPOLB | |
| Fenipentol SCHEMBL11351770 | 0.86 | LMNA (0.64) | ALDH1A1KDM4EASAH1LMNAPOLB | |
| Fenipentol SCHEMBL21837 | 0.86 | LMNA (0.64) | ALDH1A1KDM4EASAH1LMNAPOLB | |
| Phenylpropanol SCHEMBL28582184 | 0.84 | LMNA (0.70) | ALDH1A1KDM4EASAH1LMNAPOLB | |
| Fenipentol SCHEMBL29913852 | 0.84 | LMNA (0.61) | ALDH1A1KDM4EASAH1LMNAPOLB | |
| Fenipentol SCHEMBL27583052 | 0.81 | KDM4E (0.58) | ALDH1A1KDM4EASAH1LMNAPOLB | |
| Methacrylic Acid SCHEMBL1636588 | 0.81 | HPGD (0.50) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| Methacrylic Acid SCHEMBL21772120 | 0.81 | HPGD (0.50) | KDM4ELMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874601-A4 | BIOACTIVE LOAD BEARING BONE BONDING COMPOSITIONS | ORTHOVITA INC (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-0874601-A1 | BIOACTIVE LOAD BEARING BONE BONDING COMPOSITIONS | ORTHOVITA, INC. (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997020521-A1 | BIOACTIVE LOAD BEARING BONE BONDING COMPOSITIONS | ORTHOVITA, INC. (US) | 1997-06-12 | — | — | WO | disclosed |