Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011762 | 0.75 | P2RX4 (0.41) | VDRLMNACYP2D6CYP24A1P2RX4 | |
| SCHEMBL6799188 | 0.75 | CYP2D6 (0.41) | VDRLMNACYP2D6HDAC3HDAC4 | |
| SCHEMBL7490673 | 0.75 | CYP2D6 (0.39) | LMNACYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL2909081 | 0.71 | CYP24A1 (0.42) | VDRLMNACYP2D6CYP24A1HDAC3 | |
| SCHEMBL6535402 | 0.71 | VDR (0.36) | VDRLMNACYP2D6CYP24A1HDAC3 | |
| SCHEMBL9004674 | 0.70 | VDR (0.38) | VDRLMNACYP2D6GSK3BCYP1A2 | |
| Sulfuric Acid SCHEMBL9221048 | 0.69 | GSK3B (0.34) | LMNAGSK3BBCHE | |
| SCHEMBL9379877 | 0.68 | DRD2 (0.49) | LMNACYP2D6CYP24A1CYP1A2NPSR1 | |
| SCHEMBL12428132 | 0.67 | LMNA (0.50) | VDRLMNACYP2D6NPSR1 | |
| SCHEMBL12428130 | 0.67 | LMNA (0.50) | VDRLMNACYP2D6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805870-A4 | SPECTROSCOPICALLY DETECTABLE NUCLEIC ACID LIGANDS | NEXSTAR PHARMACEUTICALS INC (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-0710668-B1 | Covalent attachment of thiazole orange to oligonucleotides for use in nucleic acid detection | BECTON DICKINSON CO (US) | 2000-02-16 | — | — | EP | disclosed |
| EP-0805870-A1 | SPECTROSCOPICALLY DETECTABLE NUCLEIC ACID LIGANDS | NeXstar Pharmaceuticals, Inc. (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5650275-A | Target detection method using spectroscopically detectable nucleic acid ligands | GILEAD SCIENCES, INC. | 1997-07-22 | — | — | US | disclosed |
| US-5641629-A | MEASURING FLUORESCENCE POLARIZATION, ANISOTROPY VALUES OR ROTATIONAL CORRELATION TIMES OF LABELED NUCLEIC ACID LIGAND, ADDING TO SAMPLE, DETERMINING DIFFERENCE IN MEASURED VALUES TO INDICATE PRESENCE OF TARGET COMPOUND | GILEAD SCIENCES, INC. | 1997-06-24 | — | — | US | disclosed |
| US-5597696-A | FLUORESCENCE | BECTON DICKINSON AND COMPANY (US) | 1997-01-28 | — | — | US | disclosed |
| WO-1996022383-A1 | SPECTROSCOPICALLY DETECTABLE NUCLEIC ACID LIGANDS | NEXSTAR PHARMACEUTICALS, INC. (US) | 1996-07-25 | — | — | WO | disclosed |
| EP-0710668-A2 | Covalent attachment of thiazole orange to oligonucleotides for use in nucleic acid detection | Becton, Dickinson and Company (US) | 1996-05-08 | — | — | EP | disclosed |