Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379877 | 0.79 | DRD2 (0.49) | CYP24A1LMNACYP2D6HTR1AHTR2A | |
| SCHEMBL8861416 | 0.74 | LMNA (0.37) | LMNACYP2D6GSK3B | |
| SCHEMBL28522889 | 0.73 | VDR (0.33) | LMNAVDRCYP2D6HDAC3HDAC4 | |
| SCHEMBL6313787 | 0.72 | KDM1A (0.43) | CYP2D6HTR1AHTR2ASLC6A4HTR7 | |
| SCHEMBL890725 | 0.71 | ALDH1A1 (0.50) | CYP24A1VDRPSMD10CYP2D6 | |
| SCHEMBL483847 | 0.71 | ALDH1A1 (0.50) | CYP24A1VDRPSMD10CYP2D6 | |
| SCHEMBL29603098 | 0.70 | ALDH1A1 (0.38) | LMNACYP2D6HTR1AHTR2ASLC6A4 | |
| SCHEMBL28399716 | 0.70 | PIM1 (0.45) | LMNACYP2D6HTR1AHTR2ASLC6A4 | |
| SCHEMBL27031272 | 0.70 | KDM1A (0.53) | CYP24A1LMNACYP2D6HDAC3HDAC4 | |
| SCHEMBL10770035 | 0.70 | VDR (0.55) | CYP24A1LMNAVDRCASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217070-A1 | NUCLEIC ACID FLUORESCENT STAINS | Sigma-Aldrich Co. (US) | 2010-08-18 | — | — | EP | disclosed |
| US-20100041045-A1 | NUCLEIC ACID FLUORESCENT STAINS | SIGMA-ALDRICH CO. (US) | 2010-02-18 | — | — | US | disclosed |
| WO-2009064943-A1 | NUCLEIC ACID FLUORESCENT STAINS | SIGMA-ALDRICH CO. (US) | 2009-05-22 | — | — | WO | disclosed |
| US-20090131279-A1 | NUCLEIC ACID FLUORESCENT STAINS | SIGMA ALDRICH COMPANY (US) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131279-A1 | NUCLEIC ACID FLUORESCENT STAINS | POLRMT, HNRNPH3, EWSR1 | CYP24A1 3750/4885LMNA 180/4885VDR 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.