SCHEMBL6535929

SCHEMBL6535929

CCCCc1cc(Nc2ccccc2)ccc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
TDP1 Q9NUW8 3/20 0.43
GAA P10253 3/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
GFER P55789 1/20 0.43
ALDH1A1 P00352 7/20 0.43
ALOX12 P18054 3/20 0.43
CYP3A4 P08684 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HTT P42858 1/20 0.43
MAPK1 P28482 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
AR P10275 1/20 0.41
TLR8 Q9NR97 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30392107 1.00 MAPT (0.43) MAPTMEN1KMT2ATDP1GAA
SCHEMBL1650229 0.94 KCNH3 (0.42) MAPTMEN1KMT2ATDP1GAA
SCHEMBL8680807 0.94 KCNH3 (0.42) MAPTMEN1KMT2ATDP1GAA
SCHEMBL536379 0.90 MAPT (0.46) MAPTMEN1KMT2ATDP1GAA
SCHEMBL2904304 0.84 ALDH1A1 (0.42) MAPTMEN1KMT2ATDP1GAA
SCHEMBL3796679 0.83 MAPT (0.48) MAPTMEN1KMT2ATDP1GAA
SCHEMBL28958671 0.81 MAPT (0.46) MAPTMEN1KMT2ATDP1GAA
SCHEMBL24544158 0.80 SKP2 (0.43) MAPTMEN1KMT2ATDP1CYP3A4
SCHEMBL23609331 0.80 MAPT (0.42) MAPTMEN1KMT2ATDP1GAA
SCHEMBL1033941 0.79 NPSR1 (0.44) MAPTMEN1KMT2ATDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115678120-B Radiation-resistant magnetorheological elastomer and preparation method thereof 重庆大学 2024-01-26 CN claimed
CN-117304588-A Buffer cake rubber for locomotive and preparation method thereof 天津市橡胶工业研究所有限公司 2023-12-29 CN claimed
CN-116814028-A Heat-conducting damping rubber pad for new energy battery and preparation method 江苏迈云达科技有限公司 2023-09-29 CN claimed
CN-114163700-B Radiation-resistant nitrile rubber material for sealing nuclear power plant and preparation method thereof 陕西特种橡胶制品有限公司 2023-09-15 CN claimed
CN-115926276-A Recyclable environment-friendly rubber sole material and preparation method and recycling method thereof 北京化工大学 2023-04-07 CN claimed
CN-115678120-A Radiation-resistant magnetorheological elastomer and preparation method thereof 重庆大学 2023-02-03 CN claimed
CN-111154158-B Working sole rubber material for mine and preparation method thereof 中国皮革和制鞋工业研究院(晋江)有限公司 2022-05-24 CN claimed
CN-114163700-A Radiation-resistant nitrile rubber material for sealing nuclear power plant and preparation method thereof 陕西特种橡胶制品有限公司 2022-03-11 CN claimed
CN-114149640-A Oil-resistant ethylene propylene diene monomer hose and preparation method thereof 四川福翔科技有限公司 2022-03-08 CN claimed
CN-113749037-A Construction method of environment-friendly warming land-based fishing ground 安徽靖淮农业科技有限公司 2021-12-07 CN claimed
CN-111763355-A Thermal-oxidative-aging-resistant sidewall rubber containing silicon rubber and preparation method thereof 北京化工大学 2020-10-13 CN claimed
CN-111154158-A Working sole rubber material for mine and preparation method thereof 中国皮革和制鞋工业研究院(晋江)有限公司 2020-05-15 CN claimed
EP-4504690-A1 ANTIFOULANT COMPOSITIONS FOR VAPOR-SPACE APPLICATIONS ECOLAB USA INC. (US) 2025-02-12 EP disclosed
CN-118085426-A Tire tread rubber composition with low rolling resistance and preparation method thereof 青岛双星轮胎工业有限公司 2024-05-28 CN disclosed
CN-115536913-B Heat-resistant and aging-resistant modifier for rubber and preparation method thereof 科迈特新材料有限公司 2024-04-16 CN disclosed
CN-115710388-B Banburying method of rubber composite material 山东永丰轮胎有限公司 2024-02-23 CN disclosed
EP-1419044-A1 PROCESS AND APPARATUS FOR CONTINUOUSLY PRODUCING AN ELASTOMERIC COMPOSITION Pirelli Pneumatici S.p.A. (IT) 2004-05-19 EP disclosed
EP-1363971-A1 ELASTOMERIC COMPOSITIONS CONTAINING SURFACE TREATED BARIUM SULFATE J. M. Huber Corporation (US) 2003-11-26 EP disclosed
WO-2003009989-A1 PROCESS AND APPARATUS FOR CONTINUOUSLY PRODUCING AN ELASTOMERIC COMPOSITION PIRELLI PNEUMATICI S.P.A. (IT) 2003-02-06 WO disclosed
WO-2002014416-A1 ELASTOMERIC COMPOSITIONS CONTAINING SURFACE TREATED BARIUM SULFATE J. M. HUBER CORPORATION (US) 2002-02-21 WO disclosed