SCHEMBL536379

SCHEMBL536379

CCCc1cc(Nc2ccccc2)ccc1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
TDP1 Q9NUW8 4/20 0.46
GAA P10253 4/20 0.46
LMNA P02545 4/20 0.46
KDM4E B2RXH2 2/20 0.46
GFER P55789 1/20 0.46
ALDH1A1 P00352 9/20 0.46
CYP3A4 P08684 5/20 0.46
ALOX12 P18054 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
HTT P42858 1/20 0.46
AR P10275 1/20 0.44
HSD17B10 Q99714 5/20 0.43
ALOX15 P16050 3/20 0.43
MAPK1 P28482 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6535929 0.90 MAPT (0.43) MAPTMEN1KMT2ATDP1GAA
SCHEMBL30392107 0.90 MAPT (0.43) MAPTMEN1KMT2ATDP1GAA
SCHEMBL1650229 0.88 KCNH3 (0.42) MAPTMEN1KMT2ATDP1GAA
SCHEMBL8680807 0.88 KCNH3 (0.42) MAPTMEN1KMT2ATDP1GAA
SCHEMBL3796679 0.86 MAPT (0.48) MAPTMEN1KMT2ATDP1GAA
SCHEMBL28958671 0.83 MAPT (0.46) MAPTMEN1KMT2ATDP1GAA
SCHEMBL23609331 0.83 MAPT (0.42) MAPTMEN1KMT2ATDP1GAA
SCHEMBL2904304 0.80 ALDH1A1 (0.42) MAPTMEN1KMT2ATDP1GAA
SCHEMBL24526452 0.79 SLC18A1 (0.36) MAPTTDP1ALDH1A1CYP3A4AR
SCHEMBL3895691 0.79 ALDH1A1 (0.46) MAPTMEN1KMT2ATDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9951205-B2 Stable compositions of thiabendazole and iodine-containing fungicides LANXESS DEUTSCHLAND GMBH (DE) 2018-04-24 US disclosed
EP-2413697-B1 STABILISATION OF COMPOUNDS CONTAINING IODINE LANXESS DEUTSCHLAND GMBH (DE) 2017-11-08 EP disclosed
EP-2779830-B1 STABILIZATION OF COMPOUNDS CONTAINING IODINE HAVING POLYMERS COMPRISING NITROGEN LANXESS DEUTSCHLAND GMBH (DE) 2017-05-17 EP disclosed
US-9585384-B2 Stabilization of compounds comprising iodine LANXESS DEUTSCHLAND GMBH (DE) 2017-03-07 US disclosed
WO-2017025172-A1 RUBBER COMPOSITIONS WITH LOW CONTENT OF ZINC OXIDE HUMBOLDT-UNIVERSITÄT ZU BERLIN (DE) 2017-02-16 WO disclosed
EP-3130630-A1 RUBBER COMPOSITIONS WITH LOW CONTENT OF ZINC OXIDE Humboldt Universität zu Berlin (DE) 2017-02-15 EP disclosed
EP-3060412-A1 RUBBER COMPOSITION ARLANXEO Deutschland GmbH (DE) 2016-08-31 EP disclosed
US-9326502-B2 Stabilization of compounds containing iodine having polymers comprising nitrogen LANXESS DEUTSCHLAND GMBH (DE) 2016-05-03 US disclosed
US-9328065-B2 Nitrogen-containing inorganic carrier materials LANXESS DEUTSCHLAND GMBH (DE) 2016-05-03 US disclosed
US-9296878-B2 Fungicide formulations for plasticized PVC LANXESS DEUTSCHLAND GMBH (DE) 2016-03-29 US disclosed
EP-2236033-A1 Stabilisation of compounds containing iodine LANXESS Deutschland GmbH (DE) 2010-10-06 EP disclosed
US-20090192219-A1 STABILIZATION OF IODINE-CONTAINING BIOCIDES BY MEANS OF SPECIAL AZOLE COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2009-07-30 US disclosed
US-20090036555-A1 Stabilization of iodine biocides LANXESS DEUTSCHLAND GMBH (DE) 2009-02-05 US disclosed
EP-1993362-A1 STABILIZATION OF IODINE-CONTAINING BIOCIDES BY MEANS OF SPECIAL AZOLE COMPOUNDS Lanxess Deutschland GmbH & Co.KG (DE) 2008-11-26 EP disclosed
EP-1926367-A1 STABILIZATION OF IODINE BIOCIDES Lanxess Deutschland GmbH & Co.KG (DE) 2008-06-04 EP disclosed
WO-2007101549-A1 STABILIZATION OF IODINE-CONTAINING BIOCIDES BY MEANS OF SPECIAL AZOLE COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2007-09-13 WO disclosed
WO-2007028527-A1 STABILIZATION OF IODINE BIOCIDES LANXESS DEUTSCHLAND GMBH (DE) 2007-03-15 WO disclosed
EP-0251791-B1 ELASTOMERIC COMPOSITIONS BICC Public Limited Company (GB) 1992-01-15 EP disclosed
EP-0302007-A1 Hydroxyether-carboxylic acids and lactones thereof, process for their production and their use as corrosion inhibitors CIBA-GEIGY AG (CH) 1989-02-01 EP disclosed
EP-0251792-A2 Elastomeric compositions and methods of making them BICC Public Limited Company (GB) 1988-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036555-A1 Stabilization of iodine biocides LCT, BTD, HDHD5 MAPT 592/4885MEN1 4571/4885KMT2A 217/4885
US-20090192219-A1 STABILIZATION OF IODINE-CONTAINING BIOCIDES BY MEANS OF SPECIAL AZOLE COMPOUNDS LCT, BTD, ALKBH3 MAPT 666/4885MEN1 1981/4885KMT2A 608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.