Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979153 | 0.91 | ALDH1A1 (0.38) | SELLSELPSELETP53CYP2D6 | |
| SCHEMBL1246437 | 0.79 | LMNA (0.42) | TP53CYP2D6CYP2C9ALOX15CYP2C19 | |
| SCHEMBL11779177 | 0.78 | CA2 (0.37) | SELLSELPSELETP53CYP2D6 | |
| SCHEMBL15541782 | 0.76 | LMNA (0.53) | TP53CYP2D6CYP2C9ALOX15CYP2C19 | |
| SCHEMBL14493502 | 0.73 | ALOX15 (0.46) | SELLSELPSELETP53CYP2D6 | |
| SCHEMBL6065582 | 0.73 | CYP2C9 (0.39) | SELLSELPSELETP53CYP2D6 | |
| SCHEMBL17265722 | 0.73 | CA1 (0.47) | TP53CYP2D6CYP2C9ALOX15CYP2C19 | |
| SCHEMBL13640212 | 0.73 | CA1 (0.47) | CA2CA1 | |
| SCHEMBL29358673 | 0.71 | ALOX15 (0.47) | SELLSELPSELETP53CYP2D6 | |
| SCHEMBL39508 | 0.71 | ALOX15 (0.47) | SELLSELPSELETP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446394-A1 | NOVEL 1,2,4−THIADIAZOLE DERIVATIVES AS MELANOCORTIN RECEPTOR MODULATORS | Ortho-Mcneil Pharmaceutical Corp. (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1444215-A1 | NOVEL 1,2,4-THIADIAZOLIUM DERIVATIVES AS MELANOCORTIN RECEPTOR MODULATORS | Ortho-Mcneil Pharmaceutical Corp. (US) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003040118-A1 | NOVEL 1,2,4-THIADIAZOLIUM DERIVATIVES AS MELANOCORTIN RECEPTOR MODULATORS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003040117-A1 | NOVEL 1,2,4-THIADIAZOLE DERIVATIVES AS MELANOCORTIN RECEPTOR MODULATORS | ORTHO-MCNEIL PHARMACEUTICAL CORPORATION (US) | 2003-05-15 | — | — | WO | disclosed |
| EP-1093487-A1 | OXYGEN SCAVENGING COMPOSITION AND METHOD OF USING SAME | Cryovac, Inc. (US) | 2001-04-25 | — | — | EP | disclosed |
| WO-2000000538-A1 | OXYGEN SCAVENGING COMPOSITION AND METHOD OF USING SAME | CRYOVAC, INC. (US) | 2000-01-06 | — | — | WO | disclosed |