Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694341 | 0.92 | TK1 (0.43) | TK1TYMP | |
| SCHEMBL28239487 | 0.90 | TK1 (0.41) | TK1ALDH1A1TYMPLMNAALB | |
| SCHEMBL27651863 | 0.90 | TK1 (0.41) | TK1TYMP | |
| SCHEMBL11309914 | 0.88 | LMNA (0.47) | TK1LMNAADRA1A | |
| SCHEMBL28293851 | 0.87 | TK1 (0.39) | TK1ALDH1A1NPSR1TYMP | |
| SCHEMBL17224727 | 0.86 | TK1 (0.39) | TK1ALDH1A1NPSR1TYMP | |
| SCHEMBL5148089 | 0.85 | RNASE1 (0.46) | TK1TYMP | |
| SCHEMBL8744125 | 0.85 | TK1 (0.38) | TK1TYMP | |
| SCHEMBL8744135 | 0.84 | TK1 (0.38) | TK1 | |
| SCHEMBL5709920 | 0.84 | TK1 (0.40) | TK1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466004-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS | Innovate Biotechnology S.R.L. (IT) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057894-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS | INNOVATE BIOTECHNOLOGY S.R.L. (IT) | 2003-07-17 | — | — | WO | disclosed |
| EP-0548189-A1 | A METHOD OF LINKING NUCLEOSIDES WITH A SILOXANE BRIDGE. | STERLING WINTHROP INC (US) | 1993-06-30 | — | — | EP | disclosed |
| US-5138045-A | POLYAMINE CONJUGATED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992004364-A1 | A METHOD OF LINKING NUCLEOSIDES WITH A SILOXANE BRIDGE | STERLING WINTHROP INC. (US) | 1992-03-19 | — | — | WO | disclosed |