Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 4/20 | 0.38 |
| ▸ | TK2 | O00142 | 3/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709920 | 0.91 | TK1 (0.40) | RNASE1TK1TK2TYMP | |
| SCHEMBL29927067 | 0.89 | RNASE1 (0.39) | RNASE1TK1TK2 | |
| SCHEMBL3694341 | 0.88 | TK1 (0.43) | RNASE1TK1TYMP | |
| SCHEMBL7040496 | 0.87 | TYMS (0.37) | RNASE1TK1 | |
| SCHEMBL6536213 | 0.85 | TK1 (0.42) | TK1TYMP | |
| SCHEMBL28239487 | 0.84 | TK1 (0.41) | TK1TYMP | |
| SCHEMBL27651863 | 0.84 | TK1 (0.41) | TK1TK2TYMP | |
| SCHEMBL8377337 | 0.84 | LGALS3 (0.38) | RNASE1TK1 | |
| SCHEMBL8744201 | 0.83 | RNASE1 (0.40) | RNASE1TK1TK2 | |
| SCHEMBL28293851 | 0.82 | TK1 (0.39) | RNASE1TK1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047781-C | Process for preparing AZT and derivatives thereof | BRISTOL MYERS SQUIBB CO (US) | 1999-12-29 | — | — | CN | claimed |
| CN-117412983-A | Chimeric nucleic acid oligomer comprising phosphorothioate and borazine phosphate, and method for producing same | 学校法人东京理科大学 | 2024-01-16 | — | — | CN | disclosed |
| WO-2020219853-A1 | HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY | Molecular Assemblies, Inc. (US) | 2020-10-29 | — | — | WO | disclosed |
| EP-1831238-A2 | FLUOROUS OLIGONUCLEOTIDE REAGENTS AND AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | Berry & Associates , Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006081035-A2 | FLUOROUS OLIGONUCLEOTIDE REAGENTS AND AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | BERRY & ASSOCIATES, INC. (US) | 2006-08-03 | — | — | WO | disclosed |
| WO-2001002417-A1 | NUCLEOTIDE MONOMER CONTAINING SIX-MEMBERED AZARSUGAR AND ANTISENSE OLIGOMERS THEREOF | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-01-11 | — | — | WO | disclosed |
| US-5449664-A | Nucleosides | SYNTEX (U.S.A.) INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0457326-A1 | Antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1991-11-21 | — | — | EP | disclosed |
| EP-0371366-A1 | Antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1990-06-06 | — | — | EP | disclosed |