Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537945 | 0.79 | SMN1; SMN2 (0.40) | LMNAKDM4EALDH1A1 | |
| SCHEMBL6538051 | 0.78 | G6PD (0.43) | LMNAG6PDKDM4EPDE10AALDH1A1 | |
| SCHEMBL6537704 | 0.71 | LMNA (0.42) | LMNAKDM4EPDE10A | |
| SCHEMBL6537737 | 0.70 | PTGES (0.44) | — | |
| SCHEMBL19783367 | 0.66 | LMNA (0.36) | LMNAKDM4EPDE10AHPGD | |
| SCHEMBL30189732 | 0.66 | LMNA (0.36) | LMNAKDM4EPDE10AHPGD | |
| SCHEMBL6537788 | 0.65 | G6PD (0.39) | G6PDKDM4EPDE10AALDH1A1 | |
| SCHEMBL23534461 | 0.64 | LMNA (0.42) | LMNAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL30060571 | 0.64 | LMNA (0.42) | LMNAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL20465809 | 0.64 | LMNA (0.55) | LMNAKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |